PIP4K2A 抗体 (C-Term)
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- 抗原 See all PIP4K2A 抗体
- PIP4K2A (Phosphatidylinositol-5-Phosphate 4-Kinase, Type II, alpha (PIP4K2A))
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抗原表位
- AA 303-335, C-Term
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This PIP4K2A antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- 预测反应
- M, Pig, Rat
- 纯化方法
- This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
- 免疫原
- This PIP4K2 Alpha (PIP4K2A) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 303-335 amino acids from the C-terminal region of human PIP4K2 Alpha (PIP4K2A).
- 克隆位点
- RB1741
- 亚型
- Ig Fraction
- Top Product
- Discover our top product PIP4K2A Primary Antibody
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- 应用备注
- WB: 1:1000. IHC-P: 1:50~100
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 储存方法
- Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
- 有效期
- 6 months
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PtdIns5P is an oxidative stress-induced second messenger that regulates PKB activation." in: FASEB journal : official publication of the Federation of American Societies for Experimental Biology, Vol. 27, Issue 4, pp. 1644-56, (2013) (PubMed).
: "Regulation of phosphatidylinositol-5-phosphate signaling by Pin1 determines sensitivity to oxidative stress." in: Science signaling, Vol. 5, Issue 252, pp. ra86, (2012) (PubMed).
: "Light-induced tyrosine phosphorylation of rod outer segment membrane proteins regulate the translocation, membrane binding and activation of type II ? phosphatidylinositol-5-phosphate 4-kinase." in: Neurochemical research, Vol. 36, Issue 4, pp. 627-35, (2011) (PubMed).
: "PIP4Kbeta interacts with and modulates nuclear localization of the high-activity PtdIns5P-4-kinase isoform PIP4Kalpha." in: The Biochemical journal, Vol. 430, Issue 2, pp. 223-35, (2010) (PubMed).
: "Regulation of extranuclear PtdIns5P production by phosphatidylinositol phosphate 4-kinase 2alpha." in: FEBS letters, Vol. 582, Issue 9, pp. 1391-4, (2008) (PubMed).
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PtdIns5P is an oxidative stress-induced second messenger that regulates PKB activation." in: FASEB journal : official publication of the Federation of American Societies for Experimental Biology, Vol. 27, Issue 4, pp. 1644-56, (2013) (PubMed).
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- 抗原
- PIP4K2A (Phosphatidylinositol-5-Phosphate 4-Kinase, Type II, alpha (PIP4K2A))
- 别名
- PIP5K2 Alpha (PIP5K2A) (PIP4K2A 产品)
- 别名
- PI5P4KA antibody, PIP5K2A antibody, PIP5KII-alpha antibody, PIP5KIIA antibody, PIPK antibody, AW742916 antibody, Pip5k2a antibody, pipk antibody, pi5p4ka antibody, pip5k2a antibody, pip5kiia antibody, pip4k2a antibody, zgc:194746 antibody, zgc:194777 antibody, phosphatidylinositol-5-phosphate 4-kinase type 2 alpha antibody, phosphatidylinositol-5-phosphate 4-kinase, type II, alpha antibody, phosphatidylinositol-5-phosphate 4-kinase, type II, alpha S homeolog antibody, phosphatidylinositol-5-phosphate 4-kinase, type II, alpha a antibody, PIP4K2A antibody, Pip4k2a antibody, pip4k2a.S antibody, pip4k2a antibody, pip4k2aa antibody
- 背景
- Phosphatidylinositol-4,5-bisphosphate, the precursor to second messengers of the phosphoinositide signal transduction pathways, is thought to be involved in the regulation of secretion, cell proliferation, differentiation, and motility. TPIP5K2A is one of a family of enzymes capable of catalyzing the phosphorylation of phosphatidylinositol-4-phosphate on the fifth hydroxyl of the myo-inositol ring to form phosphatidylinositol-4,5-bisphosphate. The amino acid sequence of this enzyme does not show homology to other kinases, but the recombinant protein does exhibit kinase activity. The protein is a member of the phosphatidylinositol-4-phosphate 5-kinase family.
- 分子量
- 46225
- 基因ID
- 5305
- NCBI登录号
- NP_005019
- UniProt
- P48426
- 途径
- Inositol Metabolic Process
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