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MYLK 抗体 (N-Term)

Name: MYLK 抗体 (N-Term)
SKU: ABIN392495
Availability: OutOfStock

MYLK 适用: 人, 小鼠 WB 宿主: 兔 Polyclonal RB03067 unconjugated

MLCK Antibody (M1) (ABIN392495 and ABIN2842065) western blot analysis in SK-BR-3 cell line lysates (35 μg/lane). (MYLK 抗体 (N-Term))

Western blot analysis of anti-MLCK-long Pab (ABIN392495 and ABIN2842065) in mouse brain tissue lysate. (MYLK 抗体 (N-Term))

Western blot analysis of lysate from mouse bladder tissue lysate, using MLCKlong Antibody (M1) (ABIN392495 and ABIN2842065). (MYLK 抗体 (N-Term))

4 images

(2 references)

产品编号 ABIN392495

发货至: 中国

Datasheet as PDF

抗原 See all MYLK 抗体

MYLK (Myosin Light Chain Kinase (MYLK))
抗原表位
15

8

7

7

5

3

3

3

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
AA 923-953, N-Term
适用
78

41

36

2

2

1

1
人, 小鼠
宿主
86

4

3

1
兔
Compatible Secondaries
克隆类型
81

13
多克隆
标记
41

8

5

4

4

4

4

4

4

3

1

1

1

1

1

1

1

1

1

1

1

1

1
This MYLK antibody is un-conjugated
应用范围
38

36

25

13

13

11

5

4

4

3

2

2

1

1
Western Blotting (WB)

预测反应

Rb

纯化方法

This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

免疫原

This MLCK antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 923-953 amino acids from the N-terminal region of human MLCK.

克隆位点

RB03067

亚型

Ig Fraction

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anti-Myosin Light Chain Kinase (MYLK) (AA 1684-1884) antibody
MYLK 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated

anti-Myosin Light Chain Kinase (MYLK) (AA 1441-1709) antibody
MYLK 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated

anti-Myosin Light Chain Kinase (MYLK) (AA 1765-1914) antibody
MYLK 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated

anti-Myosin Light Chain Kinase (MYLK) (AA 908-938) antibody
MYLK 适用: 人, 小鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated

anti-Myosin Light Chain Kinase (MYLK) (AA 1661-1877) antibody
MYLK 适用: 人 WB, ELISA, IHC (p), ICC, IHC (fro) 宿主: 兔 Polyclonal unconjugated

anti-Myosin Light Chain Kinase (MYLK) antibody
MYLK 适用: 人, 小鼠, 大鼠 IHC 宿主: 兔 Polyclonal unconjugated

anti-Myosin Light Chain Kinase (MYLK) (AA 1-992) antibody
MYLK 适用: 人 WB, PLA 宿主: 兔 Polyclonal unconjugated

anti-Myosin Light Chain Kinase (MYLK) (C-Term) antibody
MYLK 适用: 人, 小鼠, 大鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated

anti-Myosin Light Chain Kinase (MYLK) (AA 290-398) antibody
MYLK 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated

应用备注

WB: 1:1000. WB: 1:1000. WB: 1:1000. WB: 1:1000

限制

仅限研究用
状态

Liquid

缓冲液

Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

储存液

Sodium azide

注意事项

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

储存条件

4 °C,-20 °C

储存方法

Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C.

有效期

6 months
Rossi, Todd, Daniels, Bazan, Belayev: "Interferon Stimulated Gene 15 upregulation precedes the development of blood brain barrier disruption and cerebral edema after traumatic brain injury in young mice." in: Journal of neurotrauma, (2015) (PubMed).

Xu, Hu, Liu, Xu, Li, Wu, Shi, Tang: "P2Y6 Receptor-Mediated Microglial Phagocytosis in Radiation-Induced Brain Injury." in: Molecular neurobiology, (2015) (PubMed).
抗原

MYLK (Myosin Light Chain Kinase (MYLK))

别名

MLCK (MYLK 产品)

别名

AAT7 antibody, KRP antibody, MLCK antibody, MLCK1 antibody, MLCK108 antibody, MLCK210 antibody, MSTP083 antibody, MYLK1 antibody, smMLCK antibody, 9530072E15Rik antibody, A930019C19Rik antibody, AW489456 antibody, Mlck antibody, SMMLCK antibody, mlck antibody, fj60a06 antibody, mlck1a antibody, mylk antibody, wu:fj60a06 antibody, zmlck1 antibody, myosin light chain kinase antibody, myosin, light polypeptide kinase antibody, myosin, light chain kinase a antibody, MYLK antibody, Mylk antibody, mylka antibody

背景

MLCK, a member of the Ser/Thr protein kinase family, is a calcium/calmodulin-dependent enzyme responsible for smooth muscle contraction via phosphorylation of a specific serine in the N-terminus of myosin light chains (MLC), an event that facilitates myosin interaction with actin filaments. It is a central determinant in the development of vascular permeability and tissue edema formation. In the nervous system it has been shown to control the growth initiation of astrocytic processes in culture and to participate in transmitter release at synapses formed between cultured sympathetic ganglion cells. MLCK acts as a critical participant in signaling sequences that result in fibroblast apoptosis. Smooth muscle and non-muscle isozymes are expressed in a wide variety of adult and fetal tissues and in cultured endothelium with qualitative expression appearing to be neither tissue- nor development-specific. Non-muscle isoform 2 is the dominant splice variant expressed in various tissues. The Telokin isoform, which binds calmodulin, has been found in a wide variety of adult and fetal tissues. MLCK is probably down-regulated by phosphorylation. The protein contains 1 fibronectin type III domain and 9 immunoglobulin-like C2-type domains.

分子量

210715

NCBI登录号

NP_444253, NP_444254, NP_444255, NP_444256, NP_444259, NP_444260

UniProt

Q15746