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- 抗原 See all PKN beta products
- PKN beta
- 抗原表位
- AA 463-492, C-Term
- 适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This PKN beta antibody is un-conjugated
- 应用范围
- Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- 纯化方法
- This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
- 免疫原
- This PKN beta antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 463-492 amino acids from the C-terminal region of human PKN beta.
- 克隆位点
- RB1043
- 亚型
- Ig Fraction
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anti-PKN beta antibody
适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- WB: 1:500. IHC-P: 1:10~50
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 储存方法
- Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
- 有效期
- 6 months
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- 抗原
- PKN beta
- Abstract
- PKN beta 产品
- 背景
- PKN3, a protein kinase C-related molecule, mediates malignant cell growth downstream of activated PI3K. PKN3 is required for invasive prostate cell growth as assessed by 3D cell culture assays and in an orthotopic mouse tumor model by inducible expression of short hairpin RNA (shRNA). PKN3 is regulated by PI3K at both the expression level and the catalytic activity level. Therefore, PKN3 might represent a preferred target for therapeutic intervention in cancers that lack tumor suppressor PTEN function or depend on chronic activation of PI3K.
- 分子量
- 99421
- 基因ID
- 29941
- NCBI登录号
- NP_037487
- UniProt
- Q6P5Z2
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