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PKD2 抗体 (C-Term)

PKD2 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal RB1352 unconjugated
产品编号 ABIN392443
发货至: 中国
  • 抗原 See all PKD2 抗体
    PKD2 (Polycystic Kidney Disease 2 (Autosomal Dominant) (PKD2))
    抗原表位
    • 15
    • 12
    • 11
    • 8
    • 7
    • 5
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 937-968, C-Term
    适用
    • 65
    • 54
    • 20
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    宿主
    • 72
    • 3
    • 1
    克隆类型
    • 74
    • 3
    多克隆
    标记
    • 40
    • 6
    • 5
    • 5
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This PKD2 antibody is un-conjugated
    应用范围
    • 42
    • 42
    • 13
    • 13
    • 11
    • 8
    • 8
    • 5
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    纯化方法
    This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
    免疫原
    This PKD2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 937-968 amino acids from the C-terminal region of human PKD2.
    克隆位点
    RB1352
    亚型
    Ig Fraction
    Top Product
    Discover our top product PKD2 Primary Antibody
  • 应用备注
    WB: 1:1000. IHC-P: 1:50~100
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
    有效期
    6 months
  • 抗原
    PKD2 (Polycystic Kidney Disease 2 (Autosomal Dominant) (PKD2))
    别名
    PKD2 (PKD2 产品)
    别名
    APKD2 antibody, PC2 antibody, PKD4 antibody, Pc-2 antibody, TRPP2 antibody, C030034P18Rik antibody, RGD1559992 antibody, pkd2 antibody, trpp2 antibody, Cup antibody, PKD2L1 antibody, polycystin 2, transient receptor potential cation channel antibody, polycystic kidney disease 2 antibody, Polycystin-2 antibody, polycystin 2, transient receptor potential cation channel L homeolog antibody, PKD2 antibody, Pkd2 antibody, pkd-2 antibody, pkd2.L antibody, pkd2 antibody
    背景
    Involved in fluid-flow mechanosensation by the primary cilium in renal epithelium. PKD1 and PKD2 may function through a common signaling pathway that is necessary for normal tubulogenesis. Acts as a regulator of cilium length, together with PKD1. The dynamic control of cilium length is essential in the regulation of mechanotransductive signaling. The cilium length response creates a negative feedback loop whereby fluid shear-mediated deflection of the primary cilium, which decreases intracellular cAMP, leads to cilium shortening and thus decreases flow-induced signaling. Functions as a calcium permeable cation channel.
    分子量
    109691
    基因ID
    25865
    NCBI登录号
    NP_000288
    UniProt
    Q13563
    途径
    cAMP Metabolic Process, Maintenance of Protein Location, Negative Regulation of Transporter Activity
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