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PIM2 抗体 (C-Term)

PIM2 适用: 人 WB, IP, IHC (p) 宿主: 兔 Polyclonal RB01288 unconjugated
产品编号 ABIN392442
发货至: 中国
  • 抗原 See all PIM2 抗体
    PIM2 (Proto-Oncogene Pim-2 (Serine Threonine Kinase) (PIM2))
    抗原表位
    • 8
    • 5
    • 5
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 277-308, C-Term
    适用
    • 42
    • 6
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    宿主
    • 34
    • 7
    • 2
    • 1
    克隆类型
    • 36
    • 8
    多克隆
    标记
    • 29
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This PIM2 antibody is un-conjugated
    应用范围
    • 30
    • 24
    • 16
    • 13
    • 8
    • 5
    • 4
    • 4
    • 1
    • 1
    Western Blotting (WB), Immunoprecipitation (IP), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    纯化方法
    This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
    免疫原
    This PIM2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 277-308 amino acids from the C-terminal region of human PIM2.
    克隆位点
    RB01288
    亚型
    Ig Fraction
    Top Product
    Discover our top product PIM2 Primary Antibody
  • 应用备注
    IP: 1:50~100. WB: 1:1000. WB: 1:1000. WB: 1:2000. IHC-P: 1:50~100
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
    有效期
    6 months
  • Pogacic, Bullock, Fedorov, Filippakopoulos, Gasser, Biondi, Meyer-Monard, Knapp, Schwaller: "Structural analysis identifies imidazo[1,2-b]pyridazines as PIM kinase inhibitors with in vitro antileukemic activity." in: Cancer research, Vol. 67, Issue 14, pp. 6916-24, (2007) (PubMed).

  • 抗原
    PIM2 (Proto-Oncogene Pim-2 (Serine Threonine Kinase) (PIM2))
    别名
    PIM2 (PIM2 产品)
    别名
    cb1068 antibody, fj47b05 antibody, pim2 antibody, wu:fj47b05 antibody, DXCch3 antibody, Pim-2 antibody, Pim-2 proto-oncogene, serine/threonine kinase antibody, proviral integration site 2 antibody, pim2 antibody, PIM2 antibody, Pim2 antibody
    背景
    Pim proteins (Pim-1, Pim-2 and Pim-3) are oncogene-encoded serine/threonine kinases. Pim-2 is highly homologous to Pim-1 with similar oncogenic functions. Pim-2 overexpression promotes resistance to a host of apoptotic stimuli, its expression is negatively regulated by growth factor depletion. Increased levels of Pim-2 has also been observed in certain cancers.
    分子量
    34190
    基因ID
    11040
    NCBI登录号
    NP_006866
    UniProt
    Q9P1W9
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