PIM1 抗体 (C-Term)
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- 抗原 See all PIM1 抗体
- PIM1 (Pim-1 Oncogene (PIM1))
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抗原表位
- AA 374-404, C-Term
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This PIM1 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- 预测反应
- B
- 纯化方法
- This antibody is purified through a protein G column, followed by dialysis against PBS.
- 免疫原
- This PIM1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 374-404 amino acids from the C-terminal region of human PIM1.
- 克隆位点
- RB1285-RB1286
- 亚型
- Ig Fraction
- Top Product
- Discover our top product PIM1 Primary Antibody
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- 应用备注
- WB: 1:1000. IHC-P: 1:50~100
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- Purified monoclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 储存方法
- Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
- 有效期
- 6 months
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Patterns and Significance of PIM Kinases in Urothelial Carcinoma." in: Applied immunohistochemistry & molecular morphology : AIMM, Vol. 23, Issue 10, pp. 717-23, (2016) (PubMed).
: "Molecular markers predicting lymph node metastasis in early esophageal cancer." in: Histology and histopathology, pp. 11618, (2015) (PubMed).
: "Prognostic impact of protein overexpression of the proto-oncogene PIM-1 in gastric cancer." in: Anticancer research, Vol. 29, Issue 11, pp. 4451-5, (2009) (PubMed).
: "Hypoxia-mediated up-regulation of Pim-1 contributes to solid tumor formation." in: The American journal of pathology, Vol. 175, Issue 1, pp. 400-11, (2009) (PubMed).
: "Hypoxia-inducible proto-oncogene Pim-1 is a prognostic marker in pancreatic ductal adenocarcinoma." in: Cancer biology & therapy, Vol. 7, Issue 9, pp. 1352-9, (2008) (PubMed).
: "Comprehensive identification of proteins in Hodgkin lymphoma-derived Reed-Sternberg cells by LC-MS/MS." in: Laboratory investigation; a journal of technical methods and pathology, Vol. 87, Issue 11, pp. 1113-24, (2007) (PubMed).
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Patterns and Significance of PIM Kinases in Urothelial Carcinoma." in: Applied immunohistochemistry & molecular morphology : AIMM, Vol. 23, Issue 10, pp. 717-23, (2016) (PubMed).
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- 抗原
- PIM1 (Pim-1 Oncogene (PIM1))
- 别名
- PIM1 (PIM1 产品)
- 别名
- PIM antibody, Pim-1 antibody, PIM1 antibody, pim antibody, pim-1 antibody, pim3 antibody, Pim-1 proto-oncogene, serine/threonine kinase antibody, proviral integration site 1 antibody, Pim-1 proto-oncogene, serine/threonine kinase L homeolog antibody, PIM1 antibody, Pim1 antibody, pim1 antibody, pim1.L antibody
- 背景
- PIM1, which belongs to the Serine/Threonine protein kinase family, is thought to play a role in signal transduction in blood cells. The protooncogene PIM1 encodes a protein kinase upregulated in prostate cancer. It may affect the structure or silencing of chromatin by phosphorylating HP1 gamma/CBX3. PIM1 is expressed primarily in cells of the hematopoietic and germ line lineages.
- 分子量
- 35686
- 基因ID
- 5292
- NCBI登录号
- NP_001230115, NP_002639
- UniProt
- P11309
- 途径
- Glycosaminoglycan Metabolic Process
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