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MAP3K10 抗体 (C-Term)

MAP3K10 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal RB0986 unconjugated
产品编号 ABIN392424
发货至: 中国
  • 抗原 See all MAP3K10 抗体
    MAP3K10 (Mitogen-Activated Protein Kinase Kinase Kinase 10 (MAP3K10))
    抗原表位
    • 8
    • 8
    • 7
    • 7
    • 6
    • 4
    • 4
    • 1
    • 1
    • 1
    AA 628-659, C-Term
    适用
    • 44
    • 22
    • 9
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    宿主
    • 41
    • 3
    克隆类型
    • 44
    多克隆
    标记
    • 19
    • 5
    • 5
    • 3
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This MAP3K10 antibody is un-conjugated
    应用范围
    • 35
    • 29
    • 26
    • 7
    • 6
    • 6
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    纯化方法
    This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
    免疫原
    This MLK2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 628-659 amino acids from the C-terminal region of human MLK2.
    克隆位点
    RB0986
    亚型
    Ig Fraction
    Top Product
    Discover our top product MAP3K10 Primary Antibody
  • 应用备注
    WB: 1:1000. IHC-P: 1:50~100
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
    有效期
    6 months
  • Humphrey, Newcomb, Yu, Hao, Yu, Krajewski, Du, Jhala: "Mixed lineage kinase-3 stabilizes and functionally cooperates with TRIBBLES-3 to compromise mitochondrial integrity in cytokine-induced death of pancreatic beta cells." in: The Journal of biological chemistry, Vol. 285, Issue 29, pp. 22426-36, (2010) (PubMed).

    Nagao, Hayashi: "Mixed lineage kinase 2 and hippocalcin are localized in Lewy bodies of Parkinson's disease." in: Journal of the neurological sciences, Vol. 281, Issue 1-2, pp. 51-4, (2009) (PubMed).

  • 抗原
    MAP3K10 (Mitogen-Activated Protein Kinase Kinase Kinase 10 (MAP3K10))
    别名
    MLK2 (MAP3K10 产品)
    别名
    MEKK10 antibody, MLK2 antibody, MST antibody, BC028668 antibody, BC046514 antibody, Mlk2 antibody, mlk2 antibody, xmlk2 antibody, mitogen-activated protein kinase kinase kinase 10 antibody, mitogen activated protein kinase kinase kinase 10 antibody, mitogen-activated protein kinase kinase kinase 10 L homeolog antibody, MAP3K10 antibody, Map3k10 antibody, map3k10.L antibody
    背景
    MLK2 is a member of the serine/threonine kinase family. This kinase has been shown to activate MAPK8/JNK and MKK4/SEK1, and this kinase itself can be phoshorylated, and thus activated by JNK kinases. This kinase functions preferentially on the JNK signaling pathway, and is reported to be involved in nerve growth factor (NGF) induced neuronal apoptosis.
    分子量
    103694
    基因ID
    4294
    NCBI登录号
    NP_002437
    UniProt
    Q02779
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