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MAP3K9 抗体 (C-Term)

MAP3K9 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal RB0983 unconjugated
产品编号 ABIN392422
发货至: 中国
  • 抗原 See all MAP3K9 抗体
    MAP3K9 (Mitogen-Activated Protein Kinase Kinase Kinase 9 (MAP3K9))
    抗原表位
    • 15
    • 15
    • 15
    • 8
    • 8
    • 6
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 1070-1104, C-Term
    适用
    • 78
    • 50
    • 25
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    宿主
    • 77
    • 1
    克隆类型
    • 78
    多克隆
    标记
    • 16
    • 7
    • 6
    • 6
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This MAP3K9 antibody is un-conjugated
    应用范围
    • 43
    • 39
    • 39
    • 29
    • 18
    • 15
    • 9
    • 2
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    纯化方法
    This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
    免疫原
    This MLK1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1070-1104 amino acids from the C-terminal region of human MLK1.
    克隆位点
    RB0983
    亚型
    Ig Fraction
    Top Product
    Discover our top product MAP3K9 Primary Antibody
  • 应用备注
    WB: 1:1000. IHC-P: 1:50~100
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
    有效期
    6 months
  • Polesskaya, Cunningham, Francis, Luebke, Zhu, Collins, Vasilyeva, Sahler, Desmet, Gelbard, Maggirwar, Walton, Frisina, Dewhurst: "Ablation of mixed lineage kinase 3 (Mlk3) does not inhibit ototoxicity induced by acoustic trauma or aminoglycoside exposure." in: Hearing research, Vol. 270, Issue 1-2, pp. 21-7, (2011) (PubMed).

    Humphrey, Newcomb, Yu, Hao, Yu, Krajewski, Du, Jhala: "Mixed lineage kinase-3 stabilizes and functionally cooperates with TRIBBLES-3 to compromise mitochondrial integrity in cytokine-induced death of pancreatic beta cells." in: The Journal of biological chemistry, Vol. 285, Issue 29, pp. 22426-36, (2010) (PubMed).

    Strath, Georgopoulos, Kellam, Blair: "Identification of genes differentially expressed as result of adenovirus type 5- and adenovirus type 12-transformation." in: BMC genomics, Vol. 10, pp. 67, (2009) (PubMed).

  • 抗原
    MAP3K9 (Mitogen-Activated Protein Kinase Kinase Kinase 9 (MAP3K9))
    别名
    MLK1 (MAP3K9 产品)
    别名
    MEKK9 antibody, MLK1 antibody, PRKE1 antibody, E130314H24Rik antibody, Mlk1 antibody, Prke1 antibody, RGD1562149 antibody, mitogen-activated protein kinase kinase kinase 9 antibody, MAP3K9 antibody, Map3k9 antibody
    背景
    MLK1 is a MLK(MAP3K) type protein kinase. The catalytic domain of mixed-lineage kinases (MLKs) kinases have amino acid sequence similarity to both the tyr-specific and the ser/thr-specific kinase classes. In addition to thee unusual nature of the kinase catalytic domains, MLK1 and MLK2 contain 2 leu/ile-zipper motifs and a basic sequence near their C-termini. MLK1 is a member of the neuronal apoptotic JNK/c-Jun pathway acting between Rac1/Cdc42 and MKK4 and -7 in death signaling. MLK1 expression has been documented in human epithelial tumor cell lines of colonic, breast and esophageal origin.
    分子量
    121895
    基因ID
    4293
    NCBI登录号
    NP_149132
    UniProt
    P80192
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