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RIPK3 抗体 (C-Term)

Name: RIPK3 抗体 (C-Term)
SKU: ABIN392275
Availability: OutOfStock

RIPK3 适用: 人, 小鼠 WB, IHC (p) 宿主: 兔 Polyclonal RB3319 unconjugated

Western blot analysis of hRIPK3- (ABIN392275 and ABIN2841945) in K562 cell line lysates (35 μg/lane). (RIPK3 抗体 (C-Term))

Formalin-fixed and paraffin-embedded human lung carcinoma tissue reacted with RIP3 (RIPK3) antibody (C-term) (ABIN392275 and ABIN2841945) , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. (RIPK3 抗体 (C-Term))

IHC (p)

Western blot analysis of hRIPK3- (ABIN392275 and ABIN2841945) in mouse cerebellum tissue lysates (35 μg/lane). (RIPK3 抗体 (C-Term))

3 images

(5 references)

产品编号 ABIN392275

发货至: 中国

Datasheet as PDF

抗原 See all RIPK3 抗体

RIPK3 (Receptor-Interacting serine-threonine Kinase 3 (RIPK3))
抗原表位
10

8

8

7

7

5

5

4

4

3

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1
AA 489-518, C-Term
适用
78

45

19

6

4

4

2

1
人, 小鼠
宿主
84

9
兔
Compatible Secondaries
克隆类型
84

9
多克隆
标记
44

9

8

7

5

5

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
This RIPK3 antibody is un-conjugated
应用范围
82

51

44

17

11

8

5

5

4

2

1
Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

纯化方法

This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

免疫原

This RIPK3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 489-518 amino acids from the C-terminal region of human RIPK3.

克隆位点

RB3319

亚型

Ig Fraction

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RIPK3 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated

anti-Receptor-Interacting serine-threonine Kinase 3 (RIPK3) (N-Term) antibody
RIPK3 适用: 人, 小鼠, 大鼠, Cow, Pig, 马, 犬 WB, IHC 宿主: 兔 Polyclonal unconjugated

anti-Receptor-Interacting serine-threonine Kinase 3 (RIPK3) (AA 61-91) antibody
RIPK3 适用: 人, 小鼠 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated

anti-Receptor-Interacting serine-threonine Kinase 3 (RIPK3) (AA 16-239) antibody
RIPK3 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated

anti-Receptor-Interacting serine-threonine Kinase 3 (RIPK3) (AA 489-518) antibody
RIPK3 适用: 人, 小鼠 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated

anti-Receptor-Interacting serine-threonine Kinase 3 (RIPK3) antibody
RIPK3 适用: 人, 小鼠, 大鼠 WB, IHC (p), IF (p) 宿主: 兔 Polyclonal unconjugated

anti-Receptor-Interacting serine-threonine Kinase 3 (RIPK3) (AA 1-217) antibody
RIPK3 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated

anti-Receptor-Interacting serine-threonine Kinase 3 (RIPK3) (AA 1-518) antibody
RIPK3 适用: 人 WB, IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated

anti-Receptor-Interacting serine-threonine Kinase 3 (RIPK3) (AA 1-120) antibody
RIPK3 适用: 人 IHC, ELISA 宿主: 兔 Polyclonal unconjugated

anti-Receptor-Interacting serine-threonine Kinase 3 (RIPK3) (AA 168-217) antibody
RIPK3 适用: 人, 猴 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated

应用备注

WB: 1:1000. WB: 1:1000. IHC-P: 1:50~100

限制

仅限研究用
状态

Liquid

缓冲液

Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

储存液

Sodium azide

注意事项

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

注意事项

Avoid freeze-thaw cycles.

储存条件

4 °C,-20 °C

储存方法

Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots.

有效期

6 months
McCullough, McMullen, Das, Roychowdhury, Strainic, Medof, Nagy: "Differential contribution of complement receptor C5aR in myeloid and non-myeloid cells in chronic ethanol-induced liver injury in mice." in: Molecular immunology, Vol. 75, pp. 122-32, (2017) (PubMed).

Deutsch, Graffeo, Rokosh, Pansari, Ochi, Levie, Van Heerden, Tippens, Greco, Barilla, Tomkötter, Zambirinis, Avanzi, Gulati, Pachter, Torres-Hernandez, Eisenthal, Daley, Miller: "Divergent effects of RIP1 or RIP3 blockade in murine models of acute liver injury." in: Cell death & disease, Vol. 6, pp. e1759, (2015) (PubMed).

Dara, Johnson, Suda, Win, Gaarde, Han, Kaplowitz: "Receptor interacting protein kinase 1 mediates murine acetaminophen toxicity independent of the necrosome and not through necroptosis." in: Hepatology (Baltimore, Md.), (2015) (PubMed).

Roychowdhury, Chiang, Mandal, McMullen, Liu, Cohen, Pollard, Feldstein, Nagy: "Inhibition of apoptosis protects mice from ethanol-mediated acceleration of early markers of CCl4 -induced fibrosis but not steatosis or inflammation." in: Alcoholism, clinical and experimental research, Vol. 36, Issue 7, pp. 1139-47, (2012) (PubMed).

Zorde-Khvalevsky, Abramovitch, Barash, Spivak-Pohis, Rivkin, Rachmilewitz, Galun, Giladi: "Toll-like receptor 3 signaling attenuates liver regeneration." in: Hepatology (Baltimore, Md.), Vol. 50, Issue 1, pp. 198-206, (2009) (PubMed).
抗原

RIPK3 (Receptor-Interacting serine-threonine Kinase 3 (RIPK3))

别名

RIPK3 (RIPK3 产品)

别名

RIPK3 antibody, RIP3 antibody, 2610528K09Rik antibody, AW107945 antibody, Rip3 antibody, Hcyp2 antibody, receptor interacting serine/threonine kinase 3 antibody, receptor interacting serine/threonine kinase 3 S homeolog antibody, receptor-interacting serine-threonine kinase 3 antibody, RIPK3 antibody, ripk3.S antibody, Ripk3 antibody

背景

RIPK3 is a member of the receptor-interacting protein (RIP) family of serine/threonine protein kinases, and contains a C-terminal domain unique from other RIP family members. The encoded protein is predominantly localized to the cytoplasm, and can undergo nucleocytoplasmic shuttling dependent on novel nuclear localization and export signals. It is a component of the tumor necrosis factor (TNF) receptor-I signaling complex, and can induce apoptosis and weakly activate the NF-kappaB transcription factor.

分子量

56887

基因ID

11035

NCBI登录号

NP_006862

UniProt

Q9Y572

途径

Activation of Innate immune Response, Toll-Like Receptors Cascades