我们推荐在您的浏览器上开启Javascript，以获得最佳效果。

ACVRL1 抗体 (N-Term)

Name: ACVRL1 抗体 (N-Term)
SKU: ABIN392241
Availability: OutOfStock

ACVRL1 适用: 人, 小鼠 WB, FACS, IHC (p) 宿主: 兔 Polyclonal RB03736 unconjugated

human chondrocytes (C28/I2 cells), transfected with empty vector (lane 1, 3) or ACVRL1(lane 2, 4). (ACVRL1 抗体 (N-Term))

Flow cytometric analysis of HepG2 cells using ACVRL1 Antibody (N-term) (bottom histogram) compared to a negative control cell (top histogram). (ACVRL1 抗体 (N-Term))

FACS

Western blot of ACVRL1 Pab (ABIN392241 and ABIN2841932). (ACVRL1 抗体 (N-Term))

Western blot analysis of ACVRL1 (arrow) using rabbit polyclonal ACVRL1 Antibody (N-term) (ABIN392241 and ABIN2841932). (ACVRL1 抗体 (N-Term))

Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. (ACVRL1 抗体 (N-Term))

IHC (p)

5 images

(4 references)

产品编号 ABIN392241

发货至: 中国

Datasheet as PDF

抗原 See all ACVRL1 抗体

ACVRL1 (Activin A Receptor Type II-Like 1 (ACVRL1))
抗原表位
8

8

6

6

6

5

2

1

1

1

1

1

1

1

1

1
AA 38-68, N-Term
适用
60

28

17

4

3

2

1

1

1
人, 小鼠
宿主
54

5

1

1
兔
Compatible Secondaries
克隆类型
52

8
多克隆
标记
39

5

4

3

2

2

1

1

1

1

1

1
This ACVRL1 antibody is un-conjugated
应用范围
50

31

30

12

11

10

3

2

2

1

1
Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

纯化方法

This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

免疫原

This ACVRL1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 38-68 amino acids from the N-terminal region of human ACVRL1.

克隆位点

RB03736

亚型

Ig Fraction
anti-Activin A Receptor Type II-Like 1 (ACVRL1) (AA 38-68) antibody
ACVRL1 适用: 人, 小鼠 WB, ELISA, IHC, FACS 宿主: 兔 Polyclonal unconjugated

anti-Activin A Receptor Type II-Like 1 (ACVRL1) antibody
ACVRL1 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated

anti-Activin A Receptor Type II-Like 1 (ACVRL1) (Internal Region) antibody
ACVRL1 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated

anti-Activin A Receptor Type II-Like 1 (ACVRL1) antibody
ACVRL1 适用: 人 WB, IF 宿主: 兔 Monoclonal unconjugated

anti-Activin A Receptor Type II-Like 1 (ACVRL1) (C-Term) antibody
ACVRL1 适用: 人, 小鼠 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated

anti-Activin A Receptor Type II-Like 1 (ACVRL1) (AA 22-118) antibody
ACVRL1 适用: 人 WB, ELISA, IF 宿主: 兔 Polyclonal unconjugated

anti-Activin A Receptor Type II-Like 1 (ACVRL1) antibody
ACVRL1 适用: 人 WB, ELISA, IHC 宿主: 兔 Monoclonal 8B6 unconjugated Recombinant Antibody

anti-Activin A Receptor Type II-Like 1 (ACVRL1) (N-Term) antibody
ACVRL1 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC (p) 宿主: 兔 Polyclonal unconjugated

anti-Activin A Receptor Type II-Like 1 (ACVRL1) (AA 22-119) antibody
ACVRL1 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 2C12 unconjugated

anti-Activin A Receptor Type II-Like 1 (ACVRL1) (AA 22-119) antibody
ACVRL1 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 5B1 unconjugated

应用备注

WB: 1:1000. WB: 1:1000. WB: 1:1000. IHC-P: 1:50~100. FC: 1:10~50

限制

仅限研究用
状态

Liquid

缓冲液

Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

储存液

Sodium azide

注意事项

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

储存条件

4 °C,-20 °C

储存方法

Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

有效期

6 months
Muñoz-Félix, Cuesta, Perretta-Tejedor, Subileau, López-Hernández, López-Novoa, Martínez-Salgado: "Identification of bone morphogenetic protein 9 (BMP9) as a novel profibrotic factor in vitro." in: Cellular signalling, Vol. 28, Issue 9, pp. 1252-61, (2017) (PubMed).

Antonov, Antonova, Fujii, ten Dijke, Handa, Catravas, Verin: "Regulation of endothelial barrier function by TGF-? type I receptor ALK5: potential role of contractile mechanisms and heat shock protein 90." in: Journal of cellular physiology, Vol. 227, Issue 2, pp. 759-71, (2011) (PubMed).

Finnson, Parker, ten Dijke, Thorikay, Philip: "ALK1 opposes ALK5/Smad3 signaling and expression of extracellular matrix components in human chondrocytes." in: Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research, Vol. 23, Issue 6, pp. 896-906, (2008) (PubMed).

Yu, Pisitkun, Wang, Shen, Knepper: "LC-MS/MS analysis of apical and basolateral plasma membranes of rat renal collecting duct cells." in: Molecular & cellular proteomics : MCP, Vol. 5, Issue 11, pp. 2131-45, (2006) (PubMed).
抗原

ACVRL1 (Activin A Receptor Type II-Like 1 (ACVRL1))

别名

ACVRL1 (ACVRL1 产品)

别名

ACVRL1 antibody, vgb antibody, alk1 antibody, zehn1109 antibody, hm:zehn1109 antibody, ACVRLK1 antibody, ALK-1 antibody, ALK1 antibody, HHT antibody, HHT2 antibody, ORW2 antibody, SKR3 antibody, TSR-I antibody, R-3 antibody, R3 antibody, SETHKIR antibody, AI115505 antibody, AI427544 antibody, Acvrlk1 antibody, Alk1 antibody, activin A receptor like type 1 antibody, activin A receptor type II-like 1 antibody, activin A receptor, type II-like 1 antibody, ACVRL1 antibody, acvrl1 antibody, Acvrl1 antibody

背景

ACVRL1 is a type I cell-surface receptor for the TGF-beta superfamily of ligands. It shares with other type I receptors a high degree of similarity in serine-threonine kinase subdomains, a glycine- and serine-rich region (called the GS domain) preceding the kinase domain, and a short C-terminal tail. This protein, sometimes termed ALK1, shares similar domain structures with other closely related ALK or activin receptor-like kinase proteins that form a subfamily of receptor serine/threonine kinases. Mutations in this gene are associated with hemorrhagic telangiectasia type 2, also known as Rendu-Osler-Weber syndrome 2.

分子量

56124

基因ID

94

NCBI登录号

NP_000011, NP_001070869

UniProt

P37023