我们推荐在您的浏览器上开启Javascript，以获得最佳效果。

alpha Actinin 4 抗体 (C-Term)

Name: alpha Actinin 4 抗体 (C-Term)
SKU: ABIN392219
Availability: OutOfStock

ACTN4 适用: 人 WB, FACS, IHC (p) 宿主: 兔 Polyclonal RB15705 unconjugated

Western blot analysis of ACTN4 Antibody (C-term) (ABIN392219 and ABIN2841915) in T47D, , , HepG2 cell line and mouse bladder tissue lysates (35 μg/lane). (alpha Actinin 4 抗体 (C-Term))

Flow cytometric analysis of MDA-231 cells using ACTN4 Antibody (C-term)(bottom histogram) compared to a negative control cell (top histogram). (alpha Actinin 4 抗体 (C-Term))

FACS

Formalin-fixed and paraffin-embedded human breast carcinoma reacted with ACTN4 Antibody (C-term), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. (alpha Actinin 4 抗体 (C-Term))

IHC (p)

3 images

(1 reference)

产品编号 ABIN392219

发货至: 中国

Datasheet as PDF

抗原 See all alpha Actinin 4 (ACTN4) 抗体

alpha Actinin 4 (ACTN4) (Actinin, alpha 4 (ACTN4))
抗原表位
10

6

6

4

4

3

2

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1
AA 785-813, C-Term
适用
91

50

46

8

5

4

4

3

3

3

2

2

1

1

1
人
宿主
84

7
兔
Compatible Secondaries
克隆类型
72

18
多克隆
标记
55

6

6

3

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1
This alpha Actinin 4 antibody is un-conjugated
应用范围
68

31

26

17

15

14

14

12

8

2

2

1

1

1

1

1

1
Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

纯化方法

This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

免疫原

This ACTN4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 785-813 amino acids from the C-terminal region of human ACTN4.

克隆位点

RB15705

亚型

Ig Fraction

Top Product

Discover our top product ACTN4 Primary Antibody
anti-Actinin, alpha 4 (ACTN4) (AA 592-701) antibody
ACTN4 适用: 人 WB, ELISA, IF, IHC (p) 宿主: 小鼠 Monoclonal 4D10 unconjugated

anti-Actinin, alpha 4 (ACTN4) (AA 1-269) antibody
ACTN4 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated

anti-Actinin, alpha 4 (ACTN4) (C-Term) antibody
ACTN4 适用: 人 WB, IF, IHC (p), ICC 宿主: 兔 Polyclonal unconjugated

anti-Actinin, alpha 4 (ACTN4) antibody
ACTN4 适用: 人 WB, IP, IF 宿主: 兔 Monoclonal unconjugated

anti-Actinin, alpha 4 (ACTN4) (AA 160-440) antibody
ACTN4 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated

anti-Actinin, alpha 4 (ACTN4) (N-Term) antibody
ACTN4 适用: 人, 小鼠, 大鼠, 犬, Cow, 豚鼠, 斑马鱼, 马, 兔 WB, IHC 宿主: 兔 Polyclonal unconjugated

anti-Actinin, alpha 4 (ACTN4) antibody
ACTN4 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated

anti-Actinin, alpha 4 (ACTN4) (AA 1-911) antibody
ACTN4 适用: 人 WB, IF, PLA 宿主: 兔 Polyclonal unconjugated

anti-Actinin, alpha 4 (ACTN4) (AA 561-661) antibody
ACTN4 适用: 人, 小鼠, 大鼠 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated

anti-Actinin, alpha 4 (ACTN4) (C-Term) antibody
ACTN4 适用: 人, 小鼠, 大鼠, 犬, Cow, 豚鼠, 斑马鱼 WB 宿主: 兔 Polyclonal unconjugated

应用备注

WB: 1:1000. IHC-P: 1:10~50. FC: 1:10~50

限制

仅限研究用
状态

Liquid

缓冲液

Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

储存液

Sodium azide

注意事项

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

储存条件

4 °C,-20 °C

储存方法

Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

有效期

6 months
Wang, Li, Wang, Tan, Jia, Yang, Li, Shang, Xu, Yang, Shoyama, Cai: "Alpha-Actinin-4 is a Possible Target Protein for Aristolochic Acid I in Human Kidney Cells In Vitro." in: The American journal of Chinese medicine, Vol. 44, Issue 2, pp. 291-304, (2016) (PubMed).
抗原

alpha Actinin 4 (ACTN4) (Actinin, alpha 4 (ACTN4))

别名

ACTN4 (ACTN4 产品)

别名

fsgs antibody, fsgs1 antibody, C77391 antibody, ACTININ-4 antibody, FSGS antibody, FSGS1 antibody, wu:fb53f05 antibody, zgc:63508 antibody, actinin alpha 4 antibody, actinin, alpha 4 antibody, actinin alpha 4 S homeolog antibody, actn4 antibody, ACTN4 antibody, Actn4 antibody, actn4.S antibody

背景

Alpha actinins belong to the spectrin superfamily which represents a diverse group of cytoskeletal proteins, including the alpha and beta spectrins and dystrophins. Alpha actinin is an actin-binding protein with multiple roles in different cell types. In nonmuscle cells, the cytoskeletal isoform is found along microfilament bundles and adherens-type junctions, where it is involved in binding actin to the membrane. In contrast, skeletal, cardiac, and smooth muscle isoforms are localized to the Z-disc and analogous dense bodies, where they help anchor the myofibrillar actin filaments. This protein is a nonmuscle, alpha actinin isoform which is concentrated in the cytoplasm, and is thought to be involved in metastatic processes. Mutations in the gene encoding this protein have been associated with focal and segmental glomerulosclerosis.

分子量

104854

基因ID

81

NCBI登录号

NP_004915

UniProt

O43707

途径

Proton Transport