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- 抗原 See all TRIB1 抗体
- TRIB1 (Tribbles Homolog 1 (TRIB1))
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抗原表位
- AA 341-370, C-Term
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This TRIB1 antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 预测反应
- M
- 纯化方法
- This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
- 免疫原
- This TRIB1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 341-370 amino acids from the C-terminal region of human TRIB1.
- 克隆位点
- RB9762
- 亚型
- Ig Fraction
- Top Product
- Discover our top product TRIB1 Primary Antibody
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- 应用备注
- WB: 1:2000. WB: 1:2000. WB: 1:1000
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 储存方法
- Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
- 有效期
- 6 months
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Sin3A-associated protein, 18 kDa, a novel binding partner of TRIB1, regulates MTTP expression." in: Journal of lipid research, Vol. 56, Issue 6, pp. 1145-52, (2015) (PubMed).
: "TRIB1 downregulates hepatic lipogenesis and glycogenesis via multiple molecular interactions." in: Journal of molecular endocrinology, Vol. 52, Issue 2, pp. 145-58, (2014) (PubMed).
: "Identification of tribbles-1 as a novel binding partner of Foxp3 in regulatory T cells." in: The Journal of biological chemistry, Vol. 288, Issue 14, pp. 10051-60, (2013) (PubMed).
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Sin3A-associated protein, 18 kDa, a novel binding partner of TRIB1, regulates MTTP expression." in: Journal of lipid research, Vol. 56, Issue 6, pp. 1145-52, (2015) (PubMed).
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- 抗原
- TRIB1 (Tribbles Homolog 1 (TRIB1))
- 别名
- TRIB1 (TRIB1 产品)
- 别名
- TRIB1 antibody, c8fw antibody, gig2 antibody, skip1 antibody, trb1 antibody, tribbles antibody, C8FW antibody, GIG2 antibody, SKIP1 antibody, TRB1 antibody, A530090O15Rik antibody, TRB-1 antibody, Trb1 antibody, Gig2 antibody, tribbles pseudokinase 1 antibody, tribbles pseudokinase 1 L homeolog antibody, tribbles homolog 1 (Drosophila) antibody, TRIB1 antibody, trib1 antibody, trib1.L antibody, Trib1 antibody
- 背景
- TRIB1 antibody, also called gprotein coupled receptor induced, skip1, gig2, c8fwATP, functions in binding protein binding, protein kinase inhibitor activity, and protein serine/threonine kinase activities. Overexpression of TRIB1 in HeLa cells repressed the basal activity of the IL8 promoter by inhibiting AP1 activity. Overexpression of TRIB1 inhibited oncogenic Ras -driven AP1 activation and MEKK1-mediated AP1 activation. ERK activation was enhanced by TRIB1. Coimmunoprecipitation and yeast 2-hybrid assays showed that MEK1 interacted with both TRIB1 and TRIB3, and MKK4 interacted specifically with TRIB1. Cotransfection of MKK4 enhanced the level of TRIB1, indicating that the TRIB-MAPKK interaction stabilized TRIB1.
- 分子量
- 41009
- 基因ID
- 10221
- NCBI登录号
- NP_079471
- UniProt
- Q96RU8
- 途径
- Smooth Muscle Cell Migration
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