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RYK 抗体 (C-Term)

RYK 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal RB1494 unconjugated
产品编号 ABIN392051
发货至: 中国
  • 抗原 See all RYK 抗体
    RYK (RYK Receptor-Like Tyrosine Kinase (RYK))
    抗原表位
    • 8
    • 7
    • 7
    • 5
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 561-591, C-Term
    适用
    • 55
    • 29
    • 16
    宿主
    • 43
    • 13
    • 3
    • 1
    克隆类型
    • 49
    • 11
    多克隆
    标记
    • 32
    • 6
    • 5
    • 5
    • 5
    • 4
    • 1
    • 1
    • 1
    This RYK antibody is un-conjugated
    应用范围
    • 54
    • 39
    • 26
    • 5
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    预测反应
    M
    纯化方法
    This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
    免疫原
    This RYK antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 561-591 amino acids from the C-terminal region of human RYK.
    克隆位点
    RB1494
    亚型
    Ig Fraction
    Top Product
    Discover our top product RYK Primary Antibody
  • 应用备注
    WB: 1:1000. IHC-P: 1:50~100
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
    有效期
    6 months
  • Santiago, Oguma, Brown, Laurence: "Noncanonical Wnt signaling promotes osteoclast differentiation and is facilitated by the human immunodeficiency virus protease inhibitor ritonavir." in: Biochemical and biophysical research communications, Vol. 417, Issue 1, pp. 223-30, (2012) (PubMed).

    Keeble, Halford, Seaman, Kee, Macheda, Anderson, Stacker, Cooper: "The Wnt receptor Ryk is required for Wnt5a-mediated axon guidance on the contralateral side of the corpus callosum." in: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 26, Issue 21, pp. 5840-8, (2006) (PubMed).

  • 抗原
    RYK (RYK Receptor-Like Tyrosine Kinase (RYK))
    别名
    RYK (RYK 产品)
    背景
    RYK is an atypical member of the family of growth factor receptor protein tyrosine kinases, differing from other members at a number of conserved residues in the activation and nucleotide binding domains. This gene product belongs to a subfamily whose members do not appear to be regulated by phosphorylation in the activation segment. It has been suggested that mediation of biological activity by recruitment of a signaling-competent auxiliary protein may occur through an as yet uncharacterized mechanism. A nine nucleotide insertion in some transcripts results in the SLG variant. It is not established whether this is a product of alternative splicing or a second gene, since evidence for a second gene or pseudogene on chromosome 17 exists.
    分子量
    67815
    基因ID
    6259
    NCBI登录号
    NP_001005861, NP_002949
    UniProt
    P34925
    途径
    RTK signaling, WNT signaling, Regulation of Cell Size
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