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ILK 抗体 (N-Term)

Name: ILK 抗体 (N-Term)
SKU: ABIN391993
Availability: OutOfStock

ILK 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal RB1668 unconjugated

Western blot analysis of anti-ILK1 Pab (ABIN391993 and ABIN2841781) in HL60 cell lysate. (ILK 抗体 (N-Term))

Formalin-fixed and paraffin-embedded human hepatocarcinoma tissue reacted with ILK1/ILK2 Antibody (N-term) (ABIN391993 and ABIN2841781) , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. (ILK 抗体 (N-Term))

IHC (p)

Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by AEC staining. (ILK 抗体 (N-Term))

IHC (p)

3 images

(2 references)

产品编号 ABIN391993

发货至: 中国

Datasheet as PDF

抗原 See all ILK 抗体

ILK (Integrin-Linked Kinase (ILK))
抗原表位
26

24

16

15

10

9

7

6

6

6

6

3

2

2

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1
AA 11-41, N-Term
适用
146

59

52

3

1

1

1

1

1

1

1

1
人
宿主
155

5

1
兔
Compatible Secondaries
克隆类型
155

6
多克隆
标记
60

14

14

12

8

8

3

3

3

3

3

3

3

3

3

3

3

2

2

2

2

2

2
This ILK antibody is un-conjugated
应用范围
108

87

54

40

39

19

17

9

6

4

4

3

2

2

1

1
Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

预测反应

B, Rat

纯化方法

This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

免疫原

This ILK1/ILK2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 11-41 amino acids from the N-terminal region of mouse ILK1/ILK2.

克隆位点

RB1668

亚型

Ig Fraction

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anti-Integrin-Linked Kinase (ILK) antibody
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应用备注

WB: 1:1000. IHC-P: 1:50~100. IHC-P: 1:50~100

限制

仅限研究用
状态

Liquid

缓冲液

Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

储存液

Sodium azide

注意事项

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

储存条件

4 °C,-20 °C

储存方法

Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

有效期

6 months
Schramm, Opitz, Thies, Seifert, Moch, Weder, Soltermann: "Prognostic significance of epithelial-mesenchymal transition in malignant pleural mesothelioma." in: European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery, Vol. 37, Issue 3, pp. 566-72, (2010) (PubMed).

Samara, Laguinge, Jessup: "Carcinoembryonic antigen inhibits anoikis in colorectal carcinoma cells by interfering with TRAIL-R2 (DR5) signaling." in: Cancer research, Vol. 67, Issue 10, pp. 4774-82, (2007) (PubMed).
抗原

ILK (Integrin-Linked Kinase (ILK))

别名

ILK1/ILK2 (ILK 产品)

别名

CG10504 antibody, CT29478 antibody, DmILK antibody, Dmel\\CG10504 antibody, ILK antibody, ilk antibody, l(3)78Ca antibody, p59 antibody, AA511515 antibody, ESTM24 antibody, zgc:65842 antibody, ILK-1 antibody, ILK-2 antibody, P59 antibody, p59ILK antibody, Integrin linked kinase antibody, integrin linked kinase antibody, integrin linked kinase S homeolog antibody, integrin-linked protein kinase antibody, integrin-linked kinase antibody, Ilk antibody, ILK antibody, ilk.S antibody, CpipJ_CPIJ016644 antibody, Bm1_20815 antibody, Tsp_07213 antibody, Tsp_07224 antibody, Tsp_15354 antibody, ilk antibody

背景

Transduction of extracellular matrix signals through integrins influences intracellular and extracellular functions, and appears to require interaction of integrin cytoplasmic domains with cellular proteins. Integrin-linked kinase (ILK), interacts with the cytoplasmic domain of beta-1 integrin. ILK encodes a predicted 451-amino acid protein, with an apparent molecular weight of 59 kD. The ILK protein is a serine/threonine protein kinase with 4 ankyrin-like repeats. ILK regulates integrin-mediated signal transduction.

分子量

51373

基因ID

16202

NCBI登录号

NP_001155196, NP_034692

UniProt

O55222

途径

Regulation of Muscle Cell Differentiation, Regulation of Cell Size, Maintenance of Protein Location, Skeletal Muscle Fiber Development, Smooth Muscle Cell Migration