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VEGFR2/CD309 抗体 (C-Term)

Name: VEGFR2/CD309 抗体 (C-Term)
SKU: ABIN391979
Availability: OutOfStock

VEGFR2 适用: 人 WB, FACS, IF, IHC (p) 宿主: 兔 Polyclonal RB01536 unconjugated

Western blot analysis of anti-KDR/FLK1 Pab (ABIN391979 and ABIN2841770) in HeLa cell lysate. (VEGFR2/CD309 抗体 (C-Term))

VEGFR2 (FLK1/KDR) Antibody (C-term) (ABIN391979 and ABIN2841770) flow cytometric analysis of MDA-M cells (right histogram) compared to a negative control cell (left histogram). (VEGFR2/CD309 抗体 (C-Term))

FACS

Confocal immunofluorescent analysis of VEGFR2 (FLK1/KDR) Antibody (C-term) (ABIN391979 and ABIN2841770) with Hela cell followed by Alexa Fluor 488-conjugated goat anti-rabbit lgG (green). (VEGFR2/CD309 抗体 (C-Term))

Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. (VEGFR2/CD309 抗体 (C-Term))

IHC (p)

4 images

(1 reference)

产品编号 ABIN391979

发货至: 中国

Datasheet as PDF

抗原 See all VEGFR2/CD309 (VEGFR2) 抗体

VEGFR2/CD309 (VEGFR2) (VEGF Receptor 2 (VEGFR2))
抗原表位
42

36

27

25

20

16

16

15

14

10

10

8

8

6

6

5

5

5

4

3

3

3

2

2

2

2

2

2

2

2

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1
AA 1326-1356, C-Term
适用
312

199

145

17

9

5

3

3

3

3

1

1

1

1

1

1

1

1

1

1
人
宿主
304

51

15

1

1

1
兔
Compatible Secondaries
克隆类型
297

76
多克隆
标记
162

34

20

13

13

12

7

7

7

7

7

7

6

6

6

6

6

6

6

6

6

6

6

2

2

1

1

1

1

1

1

1
This VEGFR2/CD309 antibody is un-conjugated
应用范围
221

135

96

84

63

26

26

22

18

14

13

12

9

8

7

4

2

2

1
Western Blotting (WB), Flow Cytometry (FACS), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

纯化方法

This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

免疫原

This VEGFR2 (FLK1/KDR) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1326-1356 amino acids from the C-terminal region of human VEGFR2 (FLK1/KDR).

克隆位点

RB01536

亚型

Ig Fraction

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anti-VEGF Receptor 2 (VEGFR2) (AA 1326-1356) antibody
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VEGFR2 适用: 人 WB, IHC (p), ICC, IHC (fro) 宿主: 兔 Polyclonal unconjugated

anti-VEGF Receptor 2 (VEGFR2) (AA 46-320) antibody
VEGFR2 适用: 大鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated

应用备注

IF: 1:10~50. WB: 1:1000. IHC-P: 1:50~100. FC: 1:10~50

限制

仅限研究用
状态

Liquid

缓冲液

Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

储存液

Sodium azide

注意事项

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

储存条件

4 °C,-20 °C

储存方法

Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

有效期

6 months
Kovács, Decatur, Toro, Pham, Liu, Jing, Murray, Lampidis, Merchan: "2-Deoxy-Glucose Downregulates Endothelial AKT and ERK via Interference with N-Linked Glycosylation, Induction of Endoplasmic Reticulum Stress, and GSK3β Activation." in: Molecular cancer therapeutics, Vol. 15, Issue 2, pp. 264-75, (2016) (PubMed).
抗原

VEGFR2/CD309 (VEGFR2) (VEGF Receptor 2 (VEGFR2))

别名

VEGFR2 (FLK1/KDR) (VEGFR2 产品)

别名

CD309 antibody, FLK1 antibody, VEGFR antibody, VEGFR2 antibody, 6130401C07 antibody, Flk-1 antibody, Flk1 antibody, Krd-1 antibody, Ly73 antibody, VEGFR-2 antibody, sVEGFR-2 antibody, Vegfr-2 antibody, FLK-1 antibody, flk-1 antibody, vegfr-2 antibody, KDR antibody, FLK/KDR antibody, flk1 antibody, flk1b antibody, kdrb antibody, si:busm1-205d10.1 antibody, si:ch211-254j6.1 antibody, si:ch211-278f21.4 antibody, wu:fc31a09 antibody, fk52c05 antibody, flk antibody, kdr antibody, kdra antibody, vegfr2 antibody, vegfr4 antibody, vegr2 antibody, wu:fk52c05 antibody, kinase insert domain receptor antibody, kinase insert domain protein receptor antibody, vascular endothelial growth factor receptor kdr-like antibody, kinase insert domain receptor (a type III receptor tyrosine kinase) antibody, kinase insert domain receptor like antibody, KDR antibody, Kdr antibody, LOC100136647 antibody, kdr antibody, kdrl antibody

背景

KDR (FLK1) is a receptor for VEGF or VEGFC. This protein has a tyrosine-protein kinase activity. The VEGF-kinase ligand/receptor signaling system plays a key role in vascular development and regulation of vascular permeability.

分子量

151527

基因ID

3791

NCBI登录号

NP_002244

UniProt

P35968

途径

RTK signaling, Glycosaminoglycan Metabolic Process, Signaling Events mediated by VEGFR1 and VEGFR2, Growth Factor Binding, Regulation of long-term Neuronal Synaptic Plasticity, VEGF Signaling