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EPH Receptor B6 抗体 (C-Term)

EPHB6 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal RB1666 unconjugated
产品编号 ABIN391928
发货至: 中国
  • 抗原 See all EPH Receptor B6 (EPHB6) 抗体
    EPH Receptor B6 (EPHB6)
    抗原表位
    • 15
    • 8
    • 8
    • 7
    • 7
    • 7
    • 7
    • 6
    • 6
    • 6
    • 6
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 990-1021, C-Term
    适用
    • 88
    • 51
    • 26
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    宿主
    • 84
    • 4
    • 1
    • 1
    克隆类型
    • 85
    • 5
    多克隆
    标记
    • 34
    • 8
    • 7
    • 6
    • 5
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This EPH Receptor B6 antibody is un-conjugated
    应用范围
    • 52
    • 42
    • 28
    • 15
    • 13
    • 11
    • 9
    • 7
    • 3
    • 2
    • 2
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    纯化方法
    This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
    免疫原
    This EphB6 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 990-1021 amino acids from the C-terminal region of human EphB6.
    克隆位点
    RB1666
    亚型
    Ig Fraction
    Top Product
    Discover our top product EPHB6 Primary Antibody
  • 应用备注
    WB: 1:1000. IHC-P: 1:50~100
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
    有效期
    6 months
  • Gu, Li, Qian, Chen, Wang, Wang: "Expression of EphB6 in ovarian serous carcinoma is associated with grade, TNM stage and survival." in: Journal of clinical pathology, (2015) (PubMed).

    Brantley-Sieders, Jiang, Sarma, Badu-Nkansah, Walter, Shyr, Chen: "Eph/ephrin profiling in human breast cancer reveals significant associations between expression level and clinical outcome." in: PLoS ONE, Vol. 6, Issue 9, pp. e24426, (2011) (PubMed).

    Yu, Bulk, Ji, Hascher, Tang, Metzger, Marra, Serve, Berdel, Wiewroth, Koschmieder, Müller-Tidow: "The EPHB6 receptor tyrosine kinase is a metastasis suppressor that is frequently silenced by promoter DNA hypermethylation in non-small cell lung cancer." in: Clinical cancer research : an official journal of the American Association for Cancer Research, Vol. 16, Issue 8, pp. 2275-83, (2010) (PubMed).

  • 抗原
    EPH Receptor B6 (EPHB6)
    别名
    EphB6 (EPHB6 产品)
    别名
    CEK9 antibody, EPHB5 antibody, Cekl antibody, Mep antibody, HEP antibody, EPH receptor B6 antibody, Eph receptor B6 antibody, EPHB6 antibody, Ephb6 antibody
    背景
    Ephrin receptors and their ligands, the ephrins, mediate numerous developmental processes, particularly in the nervous system. Based on their structures and sequence relationships, ephrins are divided into the ephrin-A (EFNA) class, which are anchored to the membrane by a glycosylphosphatidylinositol linkage, and the ephrin-B (EFNB) class, which are transmembrane proteins. The Eph family of receptors are divided into 2 groups based on the similarity of their extracellular domain sequences and their affinities for binding ephrin-A and ephrin-B ligands. Ephrin receptors make up the largest subgroup of the receptor tyrosine kinase (RTK) family. EphB6 lacks the kinase activity of most receptor tyrosine kinases and binds to ephrin-B ligands.
    分子量
    110700
    基因ID
    2051
    NCBI登录号
    NP_001267723, NP_001267724, NP_004436
    UniProt
    O15197
    途径
    RTK signaling, Hormone Transport
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