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EPH Receptor B2 抗体

EPHB2 适用: 人 WB, FACS, IHC (p) 宿主: 兔 Polyclonal RB15188 unconjugated
产品编号 ABIN391921
发货至: 中国
  • 抗原 See all EPH Receptor B2 (EPHB2) 抗体
    EPH Receptor B2 (EPHB2)
    适用
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    宿主
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    克隆类型
    • 48
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    多克隆
    标记
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    This EPH Receptor B2 antibody is un-conjugated
    应用范围
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    Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    纯化方法
    This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
    免疫原
    This EphB2 antibody is generated from rabbits immunized with a recombinant human EphB2 protein.
    克隆位点
    RB15188
    亚型
    Ig Fraction
    Top Product
    Discover our top product EPHB2 Primary Antibody
  • 应用备注
    WB: 1:1000. IHC-P: 1:10~50. FC: 1:10~50
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
    有效期
    6 months
  • 抗原
    EPH Receptor B2 (EPHB2)
    别名
    EphB2 (EPHB2 产品)
    背景
    Ephrin receptors and their ligands, the ephrins, mediate numerous developmental processes, particularly in the nervous system. Based on their structures and sequence relationships, ephrins are divided into the ephrin-A (EFNA) class, which are anchored to the membrane by a glycosylphosphatidylinositol linkage, and the ephrin-B (EFNB) class, which are transmembrane proteins. The Eph family of receptors are divided into 2 groups based on the similarity of their extracellular domain sequences and their affinities for binding ephrin-A and ephrin-B ligands. Ephrin receptors make up the largest subgroup of the receptor tyrosine kinase (RTK) family. The ligand-activated form of EphB2, which belongs to the Tyr family of protein kinases, interacts with multiple proteins, including GTPase-activating protein (RASGAP) through its SH2 domain. It binds RASGAP through the juxtamembrane tyrosines residues, and also interacts with PRKCABP and GRIP1 This type I membrane protein is expressed in brain, heart, lung, kidney, placenta, pancreas, liver and skeletal muscle. It is preferentially expressed in fetal brain. This protein contains putatively 2 fibronectin type III domains and 1 sterile alpha motif (SAM) domain.
    分子量
    117493
    基因ID
    2048
    NCBI登录号
    NP_004433, NP_059145
    UniProt
    P29323
    途径
    RTK signaling, Regulation of long-term Neuronal Synaptic Plasticity, S100 Proteins
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