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E2F1 抗体 (AA 310-344)

Name: E2F1 抗体 (AA 310-344)
SKU: ABIN391857
Availability: OutOfStock

E2F1 适用: 人 WB 宿主: 兔 Polyclonal RB08111 unconjugated

Western blot analysis of anti-E2F1 Antibody (ABIN391857 and ABIN2841688) in 293 cell line lysates (35 μg/lane). (E2F1 抗体 (AA 310-344))

1 image

(3 references)

产品编号 ABIN391857

发货至: 中国

Datasheet as PDF

抗原 See all E2F1 抗体

E2F1 (E2F Transcription Factor 1 (E2F1))
抗原表位
25

24

19

15

15

13

10

10

8

8

8

6

6

5

5

4

3

3

2

2

2

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
AA 310-344
适用
206

99

54

6

6

5

5

5

3

3

3

1

1

1
人
宿主
209

12

2
兔
Compatible Secondaries
克隆类型
201

22
多克隆
标记
92

17

17

13

10

7

5

5

5

5

5

5

5

5

5

5

5

2

2

2

2

2

2
This E2F1 antibody is un-conjugated
应用范围
187

100

67

66

51

30

22

19

18

17

15

12

6

2

1
Western Blotting (WB)

纯化方法

This antibody is purified through a protein A column, followed by peptide affinity purification.

免疫原

This E2F1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 310-344 amino acids from human E2F1.

克隆位点

RB08111

亚型

Ig Fraction

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anti-E2F Transcription Factor 1 (E2F1) (AA 101-180) antibody
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anti-E2F Transcription Factor 1 (E2F1) (AA 133-362) antibody
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anti-E2F Transcription Factor 1 (E2F1) antibody
E2F1 适用: 人 WB, IF, IP, ICC 宿主: 兔 Polyclonal unconjugated

anti-E2F Transcription Factor 1 (E2F1) (AA 342-371) antibody
E2F1 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated

anti-E2F Transcription Factor 1 (E2F1) (pSer364) antibody
E2F1 适用: 人 WB, ELISA, IF (cc), IF (p), FACS, IHC (p), ICC, IHC (fro) 宿主: 兔 Polyclonal unconjugated

anti-E2F Transcription Factor 1 (E2F1) (AA 100-170) antibody
E2F1 适用: 人, 小鼠, 大鼠 WB, ELISA, IF, IHC (p) 宿主: 兔 Polyclonal unconjugated

anti-E2F Transcription Factor 1 (E2F1) (C-Term) antibody
E2F1 适用: 人, 小鼠 WB, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated

应用备注

WB: 1:1000

限制

仅限研究用
状态

Liquid

缓冲液

Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

储存液

Sodium azide

注意事项

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

储存条件

4 °C,-20 °C

储存方法

Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

有效期

6 months
Pozner, Terooatea, Buck-Koehntop: "Cell-specific Kaiso (ZBTB33) Regulation of Cell Cycle through Cyclin D1 and Cyclin E1." in: The Journal of biological chemistry, Vol. 291, Issue 47, pp. 24538-24550, (2017) (PubMed).

Zhang, Lu, Liu, Cui, Wang: "Primate-specific miR-603 is implicated in the risk and pathogenesis of Alzheimer's disease." in: Aging, Vol. 8, Issue 2, pp. 272-90, (2016) (PubMed).

Song, Gong, Yan, Hong, Wang, Wu, Li, Li, Cao: "Sj7170, a unique dual-function peptide with a specific ?-chymotrypsin inhibitory activity and a potent tumor-activating effect from scorpion venom." in: The Journal of biological chemistry, Vol. 289, Issue 17, pp. 11667-80, (2014) (PubMed).
抗原

E2F1 (E2F Transcription Factor 1 (E2F1))

别名

E2F1 (E2F1 产品)

别名

CG6376 antibody, DRTF1/E2F antibody, DmE2F-1 antibody, Dmel\\CG6376 antibody, Dp antibody, E(Sev-CycE)3A antibody, E(var)3-93E antibody, E(var)3-95E antibody, E(var)93E antibody, E2F antibody, E2F-1 antibody, E2F1 antibody, E2f1 antibody, Evar(3)164 antibody, dE2F antibody, dE2F1 antibody, dE2f antibody, dE2f1 antibody, de2f1 antibody, def21 antibody, drosE2F1 antibody, e2f antibody, e2f1 antibody, l(3)07172 antibody, l(3)j3B1 antibody, l(3)j3C2 antibody, l(3)rM729 antibody, RBAP1 antibody, RBBP3 antibody, RBP3 antibody, mKIAA4009 antibody, xE2F antibody, ATE2FB antibody, E2F TRANSCRIPTION FACTOR-1 E2F1 antibody, E2F transcription factor 1 antibody, E2FB antibody, E2FB TRANSCRIPTION FACTOR antibody, E2F transcription factor 1 antibody, E2F transcription factor 1 L homeolog antibody, E2f1 antibody, E2F1 antibody, e2f1.L antibody

背景

E2F1 is a member of the E2F family of transcription factors. The E2F family plays a crucial role in the control of cell cycle and action of tumor suppressor proteins and is also a target of the transforming proteins of small DNA tumor viruses. The E2F proteins contain several evolutionally conserved domains found in most members of the family. These domains include a DNA binding domain, a dimerization domain which determines interaction with the differentiation regulated transcription factor proteins (DP), a transactivation domain enriched in acidic amino acids, and a tumor suppressor protein association domain which is embedded within the transactivation domain. This protein and another two members, E2F2 and E2F3, have an additional cyclin binding domain. This protein binds preferentially to retinoblastoma protein pRB in a cell-cycle dependent manner. It can mediate both cell proliferation and p53-dependent/independent apoptosis.

分子量

46920

基因ID

1869

NCBI登录号

NP_005216

UniProt

Q01094

途径

p53 Pathway, Cell Division Cycle, Mitotic G1-G1/S Phases, DNA Replication, M Phase, Autophagy