APOE 抗体 (C-Term)
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- 抗原 See all APOE 抗体
- APOE (Apolipoprotein E (APOE))
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抗原表位
- AA 263-292, C-Term
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适用
- 人, 小鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This APOE antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- 预测反应
- Pr, Rb
- 纯化方法
- This antibody is purified through a protein A column, followed by peptide affinity purification.
- 免疫原
- This APOE antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 263-292 amino acids from the C-terminal region of human APOE.
- 克隆位点
- RB15180
- 亚型
- Ig Fraction
- Top Product
- Discover our top product APOE Primary Antibody
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- 应用备注
- WB: 1:1000. IHC-P: 1:10~50
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 储存方法
- Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
- 有效期
- 6 months
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Apolipoprotein E interacts with hepatitis C virus nonstructural protein 5A and determines assembly of infectious particles." in: Hepatology (Baltimore, Md.), Vol. 51, Issue 1, pp. 43-53, (2009) (PubMed).
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Apolipoprotein E interacts with hepatitis C virus nonstructural protein 5A and determines assembly of infectious particles." in: Hepatology (Baltimore, Md.), Vol. 51, Issue 1, pp. 43-53, (2009) (PubMed).
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- 抗原
- APOE (Apolipoprotein E (APOE))
- 别名
- APOE (APOE 产品)
- 别名
- ad2 antibody, apoprotein antibody, im:7036787 antibody, wu:fb69a05 antibody, zgc:110064 antibody, apoe antibody, AI255918 antibody, AD2 antibody, LDLCQ5 antibody, LPG antibody, APOEA antibody, Apo-E antibody, apolipoprotein E antibody, apolipoprotein Ea antibody, apoe antibody, apoea antibody, Apoe antibody, APOE antibody
- 背景
- Chylomicron remnants and very low density lipoprotein (VLDL) remnants are rapidly removed from the circulation by receptor-mediated endocytosis in the liver. Apolipoprotein E, a main apoprotein of the chylomicron, binds to a specific receptor on liver cells and peripheral cells. ApoE is essential for the normal catabolism of triglyceride-rich lipoprotein constituents. The APOE gene is mapped to chromosome 19 in a cluster with APOC1 and APOC2. Defects in apolipoprotein E result in familial dysbetalipoproteinemia, or type III hyperlipoproteinemia (HLP III),in which increased plasma cholesterol and triglycerides are the consequence of impaired clearance of chylomicron and VLDL remnants.
- 分子量
- 36154
- 基因ID
- 348
- NCBI登录号
- NP_000032
- UniProt
- P02649
- 途径
- Regulation of Cell Size, Lipid Metabolism
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