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DYRK1B 抗体 (C-Term)

Name: DYRK1B 抗体 (C-Term)
SKU: ABIN391774
Availability: OutOfStock

DYRK1B 适用: 人, 小鼠 WB, IHC (p) 宿主: 兔 Polyclonal RB3017 unconjugated

Western blot analysis of anti-DYRKB Pab (ABIN391774 and ABIN2841635) in mouse kidney tissue lysate. (DYRK1B 抗体 (C-Term))

Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. (DYRK1B 抗体 (C-Term))

IHC (p)

2 images

(4 references)

产品编号 ABIN391774

发货至: 中国

Datasheet as PDF

抗原 See all DYRK1B 抗体

DYRK1B (Dual-Specificity tyrosine-(Y)-phosphorylation Regulated Kinase 1B (DYRK1B))
抗原表位
15

15

13

9

8

7

7

6

4

2

2

1

1

1

1

1

1

1

1
AA 561-589, C-Term
适用
62

38

3

2

1

1
人, 小鼠
宿主
73

4
兔
Compatible Secondaries
克隆类型
76

1
多克隆
标记
31

7

6

6

5

5

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
This DYRK1B antibody is un-conjugated
应用范围
70

45

13

13

12

4

4

3

2

2

1
Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

纯化方法

This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

免疫原

This DYRK1B antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 561-589 amino acids from the C-terminal region of human DYRK1B.

克隆位点

RB3017

亚型

Ig Fraction

Top Product

Discover our top product DYRK1B Primary Antibody
anti-Dual-Specificity tyrosine-(Y)-phosphorylation Regulated Kinase 1B (DYRK1B) (AA 479-569) antibody
DYRK1B 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 2E8 unconjugated

anti-Dual-Specificity tyrosine-(Y)-phosphorylation Regulated Kinase 1B (DYRK1B) (Internal Region) antibody
DYRK1B 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated

anti-Dual-Specificity tyrosine-(Y)-phosphorylation Regulated Kinase 1B (DYRK1B) (N-Term) antibody
DYRK1B 适用: 人 WB, IF, ICC 宿主: 兔 Polyclonal unconjugated

anti-Dual-Specificity tyrosine-(Y)-phosphorylation Regulated Kinase 1B (DYRK1B) (AA 35-130) antibody
DYRK1B 适用: 人 WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated

anti-Dual-Specificity tyrosine-(Y)-phosphorylation Regulated Kinase 1B (DYRK1B) (AA 1-629) antibody
DYRK1B 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated

anti-Dual-Specificity tyrosine-(Y)-phosphorylation Regulated Kinase 1B (DYRK1B) (AA 561-589) antibody
DYRK1B 适用: 人, 小鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated

anti-Dual-Specificity tyrosine-(Y)-phosphorylation Regulated Kinase 1B (DYRK1B) (AA 479-569) antibody
DYRK1B 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated

anti-Dual-Specificity tyrosine-(Y)-phosphorylation Regulated Kinase 1B (DYRK1B) (AA 1-629) antibody
DYRK1B 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated

anti-Dual-Specificity tyrosine-(Y)-phosphorylation Regulated Kinase 1B (DYRK1B) antibody
DYRK1B 适用: 人, 小鼠, Cow WB, IHC 宿主: 兔 Polyclonal unconjugated

anti-Dual-Specificity tyrosine-(Y)-phosphorylation Regulated Kinase 1B (DYRK1B) (AA 377-405) antibody
DYRK1B 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated

应用备注

WB: 1:1000. IHC-P: 1:50~100

限制

仅限研究用
状态

Liquid

缓冲液

Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

储存液

Sodium azide

注意事项

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

储存条件

4 °C,-20 °C

储存方法

Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

有效期

6 months
Gao, Zhao, Lv, Chen, Wei, Tian, Yang, Kong, Pang, Liu, Shi: "Mirk/Dyrk1B mediates G0/G1 to S phase cell cycle progression and cell survival involving MAPK/ERK signaling in human cancer cells." in: Cancer cell international, Vol. 13, Issue 1, pp. 2, (2013) (PubMed).

Gao, Yang, Yin, Hu, Liao, Miao, Pan, Li: "The involvement of FoxO in cell survival and chemosensitivity mediated by Mirk/Dyrk1B in ovarian cancer." in: International journal of oncology, Vol. 40, Issue 4, pp. 1203-9, (2012) (PubMed).

Lee, Ha, Kim, Kim, Chang, Song, Kim: "Negative feedback Inhibition of NFATc1 by DYRK1A regulates bone homeostasis." in: The Journal of biological chemistry, Vol. 284, Issue 48, pp. 33343-51, (2009) (PubMed).

Takahashi-Yanaga, Mori, Matsuzaki, Watanabe, Hirata, Miwa, Morimoto, Sasaguri: "Involvement of GSK-3beta and DYRK1B in differentiation-inducing factor-3-induced phosphorylation of cyclin D1 in HeLa cells." in: The Journal of biological chemistry, Vol. 281, Issue 50, pp. 38489-97, (2006) (PubMed).
抗原

DYRK1B (Dual-Specificity tyrosine-(Y)-phosphorylation Regulated Kinase 1B (DYRK1B))

别名

DYRK1B (DYRK1B 产品)

别名

DYRK1B antibody, MIRK antibody, Mirk antibody, DYRK1A antibody, dual specificity tyrosine phosphorylation regulated kinase 1B antibody, dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1b antibody, DYRK1B antibody, Dyrk1b antibody

背景

DYRK1B is a member of the DYRK family of protein kinases. DYRK1B contains a bipartite nuclear localization signal and is found mainly in muscle and testis. The protein is proposed to be involved in the regulation of nuclear functions. Three isoforms of DYRK1B have been identified differing in the presence of two alternatively spliced exons within the catalytic domain.

分子量

69198

基因ID

9149

NCBI登录号

NP_004705, NP_006474, NP_006475

UniProt

Q9Y463