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CDK8 抗体 (N-Term)

CDK8 适用: 人 WB 宿主: 兔 Polyclonal RB3200 unconjugated
产品编号 ABIN391759
发货至: 中国
  • 抗原 See all CDK8 抗体
    CDK8 (Cyclin-Dependent Kinase 8 (CDK8))
    抗原表位
    • 8
    • 8
    • 7
    • 7
    • 7
    • 6
    • 6
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 1-30, N-Term
    适用
    • 80
    • 44
    • 29
    • 8
    • 7
    • 5
    • 5
    • 5
    • 4
    • 4
    • 2
    • 2
    • 1
    • 1
    宿主
    • 76
    • 3
    • 1
    克隆类型
    • 69
    • 11
    多克隆
    标记
    • 40
    • 5
    • 4
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This CDK8 antibody is un-conjugated
    应用范围
    • 62
    • 29
    • 11
    • 10
    • 9
    • 8
    • 7
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB)
    预测反应
    M
    纯化方法
    This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
    免疫原
    This CDK8 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of human CDK8.
    克隆位点
    RB3200
    亚型
    Ig Fraction
    Top Product
    Discover our top product CDK8 Primary Antibody
  • 应用备注
    WB: 1:1000
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
    有效期
    6 months
  • Han, Zheng, Ge, Wang, Xiang, Wang: "Downregulation of cyclin-dependent kinase 8 by microRNA-148a suppresses proliferation and invasiveness of papillary thyroid carcinomas." in: American journal of cancer research, Vol. 7, Issue 10, pp. 2081-2090, (2018) (PubMed).

  • 抗原
    CDK8 (Cyclin-Dependent Kinase 8 (CDK8))
    别名
    CDK8 (CDK8 产品)
    别名
    K35 antibody, wu:fk95h11 antibody, cyclin dependent kinase 8 antibody, cyclin-dependent kinase 8 antibody, cyclin-dependent kinase 8 S homeolog antibody, Cyclin-dependent kinase 8 antibody, cyclin dependent kinase 19 antibody, CDK8 antibody, Cdk8 antibody, cdk8 antibody, cdk8.S antibody, cdk-8 antibody, CDK19 antibody
    背景
    CDK8 is a member of the cyclin-dependent protein kinase (CDK) family. CDK family members are highly similar to the gene products of Saccharomyces cerevisiae cdc28, and Schizosaccharomyces pombe cdc2, and are known to be important regulators of cell cycle progression. This kinase and its regulatory subunit cyclin C are components of the RNA polymerase II holoenzyme complex, which phosphorylates the carboxy-terminal domain (CTD) of the largest subunit of RNA polymerase II. This kinase has also been shown to regulate transcription by targeting the CDK7/cyclin H subunits of the general transcription initiation factor IIH (TFIIH), thus providing a link between the 'Mediator-like' protein complexes and the basal transcription machinery.
    分子量
    53284
    基因ID
    1024
    NCBI登录号
    NP_001251
    UniProt
    P49336
    途径
    Cell Division Cycle, Regulation of Lipid Metabolism by PPARalpha
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