GIPR 抗体 (N-Term)
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- 抗原 See all GIPR 抗体
- GIPR (Gastric Inhibitory Polypeptide Receptor (GIPR))
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抗原表位
- AA 7-38, N-Term
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This GIPR antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Flow Cytometry (FACS)
- 纯化方法
- This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
- 免疫原
- This GIPR antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 7-38 amino acids from the N-terminal region of human GIPR.
- 克隆位点
- RB18125
- 亚型
- Ig Fraction
- Top Product
- Discover our top product GIPR Primary Antibody
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- 应用备注
- WB: 1:1000. IHC-P: 1:10~50. FC: 1:10~50
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 储存方法
- Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
- 有效期
- 6 months
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Transgenic rescue of adipocyte glucose-dependent insulinotropic polypeptide receptor expression restores high fat diet-induced body weight gain." in: The Journal of biological chemistry, Vol. 286, Issue 52, pp. 44632-45, (2011) (PubMed).
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Transgenic rescue of adipocyte glucose-dependent insulinotropic polypeptide receptor expression restores high fat diet-induced body weight gain." in: The Journal of biological chemistry, Vol. 286, Issue 52, pp. 44632-45, (2011) (PubMed).
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- 抗原
- GIPR (Gastric Inhibitory Polypeptide Receptor (GIPR))
- 别名
- GIPR (GIPR 产品)
- 别名
- GIPR antibody, PGQTL2 antibody, GIP-R antibody, Gm1081 antibody, Gm160 antibody, Gippr antibody, RATGIPPR antibody, gastric inhibitory polypeptide receptor antibody, glucagon receptor antibody, GIPR antibody, LOC100303705 antibody, Gipr antibody
- 背景
- GIPR also called glucose-dependent insulinotropic polypeptide, is a 42-amino acid polypeptide synthesized by K cells of the duodenum and small intestine. This protein was originally identified as an activity in gut extracts that inhibited gastric acid secretion and gastrin release, but subsequently was demonstrated to stimulate insulin release potently in the presence of elevated glucose. The insulinotropic effect on pancreatic islet beta-cells was then recognized to be the principal physiologic action of GIP. Together with glucagon-like peptide-1, GIP is largely responsible for the secretion of insulin after eating. The protein is involved in several other facets of the anabolic response.
- 分子量
- 53157
- 基因ID
- 2696
- NCBI登录号
- NP_000155
- UniProt
- P48546
- 途径
- Positive Regulation of Peptide Hormone Secretion, cAMP Metabolic Process, Regulation of G-Protein Coupled Receptor Protein Signaling
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