DDR1 抗体 (AA 299-330)
Quick Overview for DDR1 抗体 (AA 299-330) (ABIN391458)
抗原
See all DDR1 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 299-330
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纯化方法
- This antibody is purified through a protein A column, followed by peptide affinity purification.
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免疫原
- This DDR1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 299-330 amino acids from the Central region of human DDR1.
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亚型
- Ig Fraction
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anti-Discoidin Domain Receptor tyrosine Kinase 1 (DDR1) (AA 299-330) antibody
DDR1 适用: 人 WB, ELISA, IHC, FACS, IF 宿主: 兔 Polyclonal unconjugated
anti-Discoidin Domain Receptor tyrosine Kinase 1 (DDR1) (AA 568-829) antibodyDDR1 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Discoidin Domain Receptor tyrosine Kinase 1 (DDR1) (AA 21-176) antibodyDDR1 适用: 人 ELISA, FACS 宿主: 小鼠 Monoclonal 4F2C12 unconjugated
anti-Discoidin Domain Receptor tyrosine Kinase 1 (DDR1) (AA 17-47), (N-Term) antibodyDDR1 适用: 人, 大鼠 WB, IHC (p), FACS 宿主: 兔 Polyclonal RB01477 unconjugated
anti-Discoidin Domain Receptor tyrosine Kinase 1 (DDR1) (AA 17-47) antibodyDDR1 适用: 人 WB, ELISA, IHC, FACS 宿主: 兔 Polyclonal unconjugated
anti-Discoidin Domain Receptor tyrosine Kinase 1 (DDR1) (AA 21-120) antibodyDDR1 适用: 大鼠, 小鼠 WB, ELISA, IHC (p), IF (p), IF (cc), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Discoidin Domain Receptor tyrosine Kinase 1 (DDR1) antibodyDDR1 适用: 人 WB, IHC (p) 宿主: 小鼠 Monoclonal 4C4 unconjugated
anti-Discoidin Domain Receptor tyrosine Kinase 1 (DDR1) (AA 396-430) antibodyDDR1 适用: 人, 小鼠 WB 宿主: 兔 Polyclonal RB50593 unconjugated
anti-Discoidin Domain Receptor tyrosine Kinase 1 (DDR1) (AA 22-876) antibodyDDR1 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-Discoidin Domain Receptor tyrosine Kinase 1 (DDR1) (Internal Region) antibodyDDR1 适用: 人, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
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应用备注
- IF: 1:10~50. WB: 1:500. IHC-P: 1:100. IHC-P: 1:100. FC: 1:10~50
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
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有效期
- 6 months
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- DDR1 (Discoidin Domain Receptor tyrosine Kinase 1 (DDR1))
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别名
- DDR1
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背景
- Receptor tyrosine kinases (RTKs) play a key role in the communication of cells with their microenvironment. These molecules are involved in the regulation of cell growth, differentiation and metabolism. DDR1 is an RTK that is widely expressed in normal and transformed epithelial cells and is activated by various types of collagen. It belongs to a subfamily of tyrosine kinase receptors with a homology region to the Dictyostelium discoideum protein discoidin I in their extracellular domain. Its autophosphorylation is achieved by all collagens so far tested (type I to type VI). In situ studies and Northern-blot analysis show that expression of DDR1 is restricted to epithelial cells, particularly in the kidney, lung, gastrointestinal tract, and brain. In addition, it is significantly over-expressed in several human tumors from breast, ovarian, esophageal, and pediatric brain.
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分子量
- 101128
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基因ID
- 780
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NCBI登录号
- NP_001189450, NP_001189451, NP_001189452, NP_001945, NP_054699, NP_054700
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UniProt
- Q08345
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途径
- RTK signaling, Smooth Muscle Cell Migration
抗原
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