SPHK2 抗体 (C-Term)
(2 references)-
- 抗原 See all SPHK2 抗体
- SPHK2 (Sphingosine Kinase 2 (SPHK2))
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抗原表位
- AA 590-620, C-Term
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This SPHK2 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- 纯化方法
- This antibody is purified through a protein A column, followed by peptide affinity purification.
- 免疫原
- This SPHK2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 590-620 amino acids from the C-terminal region of human SPHK2.
- 克隆位点
- RB03625
- 亚型
- IgG
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anti-Sphingosine Kinase 2 (SPHK2) (AA 1-654) antibody
SPHK2 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
anti-Sphingosine Kinase 2 (SPHK2) (AA 101-200) antibodySPHK2 适用: 人, 小鼠, 大鼠 ELISA, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Sphingosine Kinase 2 (SPHK2) antibodySPHK2 适用: 人, 小鼠 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Sphingosine Kinase 2 (SPHK2) (Tyr754) antibodySPHK2 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Sphingosine Kinase 2 (SPHK2) (AA 1-654) antibodySPHK2 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Sphingosine Kinase 2 (SPHK2) (N-Term) antibodySPHK2 适用: 人 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Sphingosine Kinase 2 (SPHK2) (AA 1-30), (N-Term) antibodySPHK2 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal RB03623 unconjugated
anti-Sphingosine Kinase 2 (SPHK2) (AA 1-30) antibodySPHK2 适用: 人 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Sphingosine Kinase 2 (SPHK2) (AA 590-620) antibodySPHK2 适用: 人 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Sphingosine Kinase 2 (SPHK2) (C-Term) antibodySPHK2 适用: 人, 小鼠, 大鼠 WB 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- WB: 1:1000. WB: 1:1000. IHC-P-Leica: 1:250. IHC-P-Leica: 1:250
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid freeze-thaw cycles.
- 储存条件
- 4 °C,-20 °C
- 储存方法
- Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots.
- 有效期
- 6 months
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- 抗原
- SPHK2 (Sphingosine Kinase 2 (SPHK2))
- 别名
- SPHK2 (SPHK2 产品)
- 别名
- CG2159 antibody, CG32484 antibody, Dmel\\CG32484 antibody, SK2 antibody, Sphk2 antibody, sk2 antibody, DKFZp469F224 antibody, SK 2 antibody, SK-2 antibody, SPK 2 antibody, SPK-2 antibody, C76851 antibody, Sphingosine kinase antibody, sphk2 antibody, Sphingosine kinase 2 antibody, sphingosine kinase 2 antibody, sphK2 antibody, Sk2 antibody, SPHK2 antibody, Sphk2 antibody
- 背景
- Sphingosine Kinase (SphK) catalyzes the phosphorylation of the lipid sphingosine, creating the bioactive lipid sphingosine-1-phosphate (S1P). S1P subsequently signals through cell surface G protein-coupled receptors, as well as intracellularly, to modulate cell proliferation, survival, motility and differentiation. SphK is an important signaling enzyme which is activated by diverse agents, including growth factors that signal through receptor tyrosine kinases, agents activating G protein-coupled receptors, and immunoglobulin receptors. Two SphK isotypes, SphK-1 and SphK-2, have been cloned, and both isotypes are ubiquitously expressed. SphK-1 has been shown to mediate cell growth, prevention of apoptosis, and cellular transformation, and is upregulated in a variety of human tumors. In contrast, SphK-2 increases apoptosis, and may be responsible for phosphorylating and activating the immunosuppressive drug FTY720.
- 分子量
- 69217
- NCBI登录号
- NP_001191087, NP_001191088, NP_001191089, NP_064511
- UniProt
- Q9NRA0
- 途径
- VEGF Signaling
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