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- 抗原 See all DCLK1 抗体
- DCLK1 (Doublecortin-Like Kinase 1 (DCLK1))
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抗原表位
- AA 1-30, N-Term
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适用
- 人, 小鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This DCLK1 antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 纯化方法
- This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
- 免疫原
- This DCAMKL1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of human DCAMKL1.
- 克隆位点
- RB3059
- 亚型
- Ig Fraction
- Top Product
- Discover our top product DCLK1 Primary Antibody
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- 应用备注
- WB: 1:1000. WB: 1:1000
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 储存方法
- Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
- 有效期
- 6 months
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A multicellular approach forms a significant amount of tissue-engineered small intestine in the mouse." in: Tissue engineering. Part A, Vol. 17, Issue 13-14, pp. 1841-50, (2011) (PubMed).
: "IFN-? inhibits gastric carcinogenesis by inducing epithelial cell autophagy and T-cell apoptosis." in: Cancer research, Vol. 71, Issue 12, pp. 4247-59, (2011) (PubMed).
: "Conditional deletion of IkappaB-kinase-beta accelerates helicobacter-dependent gastric apoptosis, proliferation, and preneoplasia." in: Gastroenterology, Vol. 138, Issue 3, pp. 1022-34.e1-10, (2010) (PubMed).
: "Inactivating cholecystokinin-2 receptor inhibits progastrin-dependent colonic crypt fission, proliferation, and colorectal cancer in mice." in: The Journal of clinical investigation, Vol. 119, Issue 9, pp. 2691-701, (2009) (PubMed).
: "Hepatic effects of a methionine-choline-deficient diet in hepatocyte RXRalpha-null mice." in: Toxicology and applied pharmacology, Vol. 234, Issue 2, pp. 166-78, (2009) (PubMed).
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A multicellular approach forms a significant amount of tissue-engineered small intestine in the mouse." in: Tissue engineering. Part A, Vol. 17, Issue 13-14, pp. 1841-50, (2011) (PubMed).
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- 抗原
- DCLK1 (Doublecortin-Like Kinase 1 (DCLK1))
- 别名
- DCAMKL1 (DCLK1 产品)
- 背景
- Doublecortin-like kinase (DCAMKL1)(Ser/Thr protein kinase family) is essential for proper neurogenesis, neuronal migration, and axonal wiring. DCAMKL1 is involved in a calcium-signaling pathway controling neuronal migration in the developing brain, and participates in functions of the mature nervous system. DCAMKL1 protein shares high homology with doublecortin (DCX). DCLK, but not DCX, is highly expressed in regions of active neurogenesis in the neocortex and cerebellum. DCAMKL1 controls mitotic division by regulating spindle formation and also determines the fate of neural progenitors during cortical neurogenesis.
- 分子量
- 82224
- 基因ID
- 9201
- NCBI登录号
- NP_001182344, NP_001182345, NP_004725
- UniProt
- O15075
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