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- 抗原 See all BRSK2 抗体
- BRSK2 (BR serine/threonine Kinase 2 (BRSK2))
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抗原表位
- AA 706-736, C-Term
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This BRSK2 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- 纯化方法
- This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
- 免疫原
- This STK29 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 706-736 amino acids from the C-terminal region of human STK29.
- 克隆位点
- RB5548
- 亚型
- Ig Fraction
- Top Product
- Discover our top product BRSK2 Primary Antibody
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anti-BR serine/threonine Kinase 2 (BRSK2) (Internal Region) antibody
Verified BRSK2 适用: 人 ELISA, IF, FACS 宿主: 山羊 Polyclonal unconjugated
anti-BR serine/threonine Kinase 2 (BRSK2) antibodyBRSK2 适用: 人, 小鼠, 大鼠 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-BR serine/threonine Kinase 2 (BRSK2) (AA 1-170) antibodyBRSK2 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-BR serine/threonine Kinase 2 (BRSK2) (C-Term) antibodyBRSK2 适用: 人, 小鼠 WB, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- WB: 1:1000. IHC-P: 1:50~100
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 储存方法
- Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
- 有效期
- 6 months
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- 抗原
- BRSK2 (BR serine/threonine Kinase 2 (BRSK2))
- 别名
- STK29 (BRSK2 产品)
- 别名
- C11orf7 antibody, PEN11B antibody, SAD1 antibody, SADA antibody, STK29 antibody, BRSK2 antibody, 4833424K13Rik antibody, SAD-A antibody, BR serine/threonine kinase 2 antibody, BRSK2 antibody, Brsk2 antibody
- 背景
- BRSK2 expressed in insect cells specifically phosphorylates WEE1A, CDC25C, and CDC25B in an in vitro assay, but a kinase-dead mutant does not. Overexpression of BRSK2 in HeLa cells results in increased phosphorylation of CDC25C. DNA damage induced by ultraviolet (UV) irradiation or methyl methane sulfonate, but not by ionizing radiation, enhances endogenous BRSK2 kinase activity in a caffeine-sensitive manner and causes translocation of BRSK2 from the cytoplasm to the nucleus. Overexpression of BRSK2 induces G2/M arrest in HeLa cells. Small interfering RNA against BRSK2 partly abrogates UV-induced G2/M arrest. BRSK2 may act as a checkpoint kinase upon DNA damage induced by UV irradiation or methyl methane sulfonate.
- 分子量
- 81633
- 基因ID
- 9024
- NCBI登录号
- NP_001243556, NP_001243558, NP_001243559, NP_003948
- UniProt
- Q8IWQ3
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