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RIPK3 抗体 (N-Term)

RIPK3 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal RB8631 unconjugated
产品编号 ABIN391272
发货至: 中国
  • 抗原 See all RIPK3 抗体
    RIPK3 (Receptor-Interacting serine-threonine Kinase 3 (RIPK3))
    抗原表位
    • 11
    • 8
    • 8
    • 7
    • 7
    • 5
    • 5
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 1-30, N-Term
    适用
    • 78
    • 46
    • 19
    • 6
    • 4
    • 4
    • 2
    • 1
    宿主
    • 84
    • 9
    克隆类型
    • 84
    • 9
    多克隆
    标记
    • 44
    • 9
    • 8
    • 7
    • 5
    • 5
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This RIPK3 antibody is un-conjugated
    应用范围
    • 82
    • 51
    • 44
    • 17
    • 11
    • 8
    • 5
    • 5
    • 4
    • 2
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    纯化方法
    This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
    免疫原
    This RIPK3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of human RIPK3.
    克隆位点
    RB8631
    亚型
    Ig Fraction
    Top Product
    Discover our top product RIPK3 Primary Antibody
  • 应用备注
    WB: 1:1000. IHC-P: 1:10~50
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
    有效期
    6 months
  • Viringipurampeer, Metcalfe, Bashar, Sivak, Yanai, Mohammadi, Moritz, Gregory-Evans, Gregory-Evans: "NLRP3 inflammasome activation drives bystander cone photoreceptor cell death in a P23H rhodopsin model of retinal degeneration." in: Human molecular genetics, Vol. 25, Issue 8, pp. 1501-16, (2016) (PubMed).

    Viringipurampeer, Ferreira, DeMaria, Yoon, Shan, Moosajee, Gregory-Evans, Ngai, Gregory-Evans: "Pax2 regulates a fadd-dependent molecular switch that drives tissue fusion during eye development." in: Human molecular genetics, Vol. 21, Issue 10, pp. 2357-69, (2012) (PubMed).

  • 抗原
    RIPK3 (Receptor-Interacting serine-threonine Kinase 3 (RIPK3))
    别名
    RIPK3 (RIPK3 产品)
    别名
    RIPK3 antibody, RIP3 antibody, 2610528K09Rik antibody, AW107945 antibody, Rip3 antibody, Hcyp2 antibody, receptor interacting serine/threonine kinase 3 antibody, receptor interacting serine/threonine kinase 3 S homeolog antibody, receptor-interacting serine-threonine kinase 3 antibody, RIPK3 antibody, ripk3.S antibody, Ripk3 antibody
    背景
    The product of this gene is a member of the receptor-interacting protein (RIP) family of serine/threonine protein kinases, and contains a C-terminal domain unique from other RIP family members. The encoded protein is predominantly localized to the cytoplasm, and can undergo nucleocytoplasmic shuttling dependent on novel nuclear localization and export signals. It is a component of the tumor necrosis factor (TNF) receptor-I signaling complex, and can induce apoptosis and weakly activate the NF-kappaB transcription factor.
    分子量
    56887
    基因ID
    11035
    NCBI登录号
    NP_006862
    UniProt
    Q9Y572
    途径
    Activation of Innate immune Response, Toll-Like Receptors Cascades
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