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PDXK 抗体 (C-Term)

Name: PDXK 抗体 (C-Term)
SKU: ABIN391248
Availability: OutOfStock

PDXK 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal RB5462 unconjugated

Western blot analysis of anti-PDXK (ABIN391248 and ABIN2841310) in HepG2 cell line lysate (35 μg/lane). (PDXK 抗体 (C-Term))

Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. (PDXK 抗体 (C-Term))

IHC (p)

2 images

产品编号 ABIN391248

发货至: 中国

Datasheet as PDF

抗原 See all PDXK 抗体

PDXK (Pyridoxal Kinase (PDXK))
抗原表位
8

8

3

1

1

1

1

1

1

1

1

1

1
AA 242-272, C-Term
适用
52

31

21

4

4

3

3

3

2

2

1

1

1
人
宿主
45

10
兔
Compatible Secondaries
克隆类型
47

8
多克隆
标记
30

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
This PDXK antibody is un-conjugated
应用范围
47

13

13

11

7

5

4

4

3

1
Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

纯化方法

This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

免疫原

This PDXK antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 242-272 amino acids from the C-terminal region of human PDXK.

克隆位点

RB5462

亚型

Ig Fraction

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anti-Pyridoxal Kinase (PDXK) (AA 1-312) antibody
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anti-Pyridoxal Kinase (PDXK) antibody
PDXK 适用: 人, 小鼠, 大鼠 WB, IF 宿主: 兔 Polyclonal unconjugated

anti-Pyridoxal Kinase (PDXK) (AA 1-312) antibody
PDXK 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated

应用备注

WB: 1:1000. IHC-P: 1:50~100

限制

仅限研究用
状态

Liquid

缓冲液

Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

储存液

Sodium azide

注意事项

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

储存条件

4 °C,-20 °C

储存方法

Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

有效期

6 months
抗原

PDXK (Pyridoxal Kinase (PDXK))

别名

PDXK (PDXK 产品)

别名

C21orf124 antibody, C21orf97 antibody, PKH antibody, PNK antibody, 2310036D04Rik antibody, AA119688 antibody, C77999 antibody, Pdxk antibody, PSPTO5521 antibody, DDBDRAFT_0190079 antibody, DDBDRAFT_0191114 antibody, DDB_0190079 antibody, DDB_0191114 antibody, ATSOS4 antibody, K18L3.1 antibody, K18L3_1 antibody, SALT OVERLY SENSITIVE 4 antibody, pdxk antibody, si:dkey-263m10.2 antibody, si:dz69g10.1 antibody, cb1056 antibody, pdxkl antibody, si:dkey-281i8.2 antibody, wu:fa55a03 antibody, wu:fb10c12 antibody, zgc:101900 antibody, pyridoxal kinase antibody, pyridoxal (pyridoxine, vitamin B6) kinase antibody, Pyridoxal kinase antibody, pfkB-like carbohydrate kinase family protein antibody, pyridoxal (pyridoxine, vitamin B6) kinase b antibody, pyridoxal (pyridoxine, vitamin B6) kinase a antibody, PDXK antibody, Pdxk antibody, pdxY antibody, pdxK antibody, Bphyt_1541 antibody, pykA antibody, Kfla_4736 antibody, Kvar_1290 antibody, Mrub_2507 antibody, BC1002_1103 antibody, Fbal_1661 antibody, Lbys_0710 antibody, Intca_0131 antibody, Deima_3190 antibody, Mesop_1158 antibody, LOC100283562 antibody, pdxk antibody, SOS4 antibody, pdxkb antibody, pdxka antibody

背景

Pyridoxal kinase (PDXK) converts vitamin B6 to pyridoxal-5-phosphate (PLP), an essential cofactor in the intermediate metabolism of amino acids and neurotransmitters. The PDXK gene encodes a 312-amino acid polypeptide, and expression of the cDNA reveals pyridoxal kinase activity. Northern blot analysis revealed that a major 1.5-kb PDXK transcript is expressed in all tissues tested. The expression of PDXK shows circadian oscillations. The expression of Pdxk in mouse liver and brain is regulated by the 3 PAR bZIP transcription factors, Dbp, Hlf, and Tef, which also show circadian oscillations in expression. Mice devoid of all 3 transcription factors show decreased levels of brain PLP, serotonin, and dopamine, and are highly susceptible to frequently lethal generalized spontaneous and audiogenic epilepsies.

分子量

35102

基因ID

8566

NCBI登录号

NP_003672

UniProt

O00764