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NME3 抗体 (AA 51-81)

NME3 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal RB5454 unconjugated
产品编号 ABIN391232
发货至: 中国
  • 抗原 See all NME3 抗体
    NME3 (NME/NM23 Nucleoside Diphosphate Kinase 3 (NME3))
    抗原表位
    • 6
    • 6
    • 5
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    AA 51-81
    适用
    • 34
    • 11
    • 2
    宿主
    • 30
    • 5
    克隆类型
    • 32
    • 3
    多克隆
    标记
    • 18
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This NME3 antibody is un-conjugated
    应用范围
    • 19
    • 15
    • 14
    • 5
    • 5
    • 4
    • 2
    • 2
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    纯化方法
    This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
    免疫原
    This NME3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 51-81 amino acids from the Central region of human NME3.
    克隆位点
    RB5454
    亚型
    Ig Fraction
    Top Product
    Discover our top product NME3 Primary Antibody
  • 应用备注
    WB: 1:1000. IHC-P: 1:50~100
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
    有效期
    6 months
  • 抗原
    NME3 (NME/NM23 Nucleoside Diphosphate Kinase 3 (NME3))
    别名
    NME3 (NME3 产品)
    别名
    DR-nm23 antibody, NDPK-C antibody, NDPKC antibody, NM23-H3 antibody, NM23H3 antibody, c371H6.2 antibody, 1810009F08Rik antibody, AI413736 antibody, Ndk3 antibody, Nm23-DR antibody, Nm23-M3 antibody, NME/NM23 nucleoside diphosphate kinase 3 antibody, NME3 antibody, Nme3 antibody
    背景
    NME3 mRNA is preferentially expressed at early stages of myeloid differentiation of highly purified CD34(+) cells. Its constitutive expression in a myeloid precursor line, which is growth-factor dependent for both proliferation and differentiation, results in inhibition of granulocytic differentiation induced by granulocyte colony-stimulating factor and causes apoptotic cell death. These results appear consistent with a role for the NME3 gene in normal hematopoiesis and raise the possibility that its overexpression contributes to differentiation arrest, a feature of blastic transformation in chronic myelogenous leukemia.
    分子量
    19015
    基因ID
    4832
    NCBI登录号
    NP_002504
    UniProt
    Q13232
    途径
    Nucleotide Phosphorylation, Ribonucleoside Biosynthetic Process
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