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ERN2 抗体 (N-Term)

ERN2 适用: 人 WB 宿主: 兔 Polyclonal RB8519 unconjugated
产品编号 ABIN391194
发货至: 中国
  • 抗原 See all ERN2 抗体
    ERN2 (Endoplasmic Reticulum To Nucleus Signaling 2 (ERN2))
    抗原表位
    • 17
    • 9
    • 6
    • 6
    • 2
    • 1
    • 1
    • 1
    • 1
    AA 39-72, N-Term
    适用
    • 28
    • 19
    宿主
    • 43
    • 1
    克隆类型
    • 44
    多克隆
    标记
    • 17
    • 5
    • 4
    • 4
    • 4
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This ERN2 antibody is un-conjugated
    应用范围
    • 31
    • 31
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB)
    纯化方法
    This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
    免疫原
    This ERN2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 39-72 amino acids from the N-terminal region of human ERN2.
    克隆位点
    RB8519
    亚型
    Ig Fraction
    Top Product
    Discover our top product ERN2 Primary Antibody
  • 应用备注
    WB: 1:1000. WB: 1:1000
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
    有效期
    6 months
  • 抗原
    ERN2 (Endoplasmic Reticulum To Nucleus Signaling 2 (ERN2))
    别名
    ERN2 (ERN2 产品)
    别名
    Ire1beta antibody, ire1b antibody, Ern1 antibody, Ire1 antibody, Ire1b antibody, IRE1-BETA antibody, IRE1b antibody, endoplasmic reticulum to nucleus signaling 2 antibody, endoplasmic reticulum (ER) to nucleus signalling 2 antibody, ERN2 antibody, ern2 antibody, Ern2 antibody
    背景
    ERN2 induces translational repression through 28S ribosomal RNA cleavage in response to endoplasmic reticulum (ER) stress. This pro-apoptotic appears to play no role in the unfolded-protein response, unlike closely related proteins. Overexpression of ERN2 activates both BiP and CHOP expression, and also leads to the development of programmed cell death. It has been suggested that Ern2 plays a role in multiple facets of the ER stress response in mammalian cells.
    分子量
    102480
    基因ID
    10595
    NCBI登录号
    NP_150296
    UniProt
    Q76MJ5
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