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STRADB 抗体 (C-Term)

STRADB 适用: 人 WB 宿主: 兔 Polyclonal RB15723 unconjugated
产品编号 ABIN391172
发货至: 中国
  • 抗原 See all STRADB 抗体
    STRADB (STE20-Related Kinase Adaptor beta (STRADB))
    抗原表位
    • 9
    • 8
    • 5
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 274-303, C-Term
    适用
    • 28
    • 22
    • 3
    • 1
    • 1
    • 1
    宿主
    • 36
    • 2
    • 1
    克隆类型
    • 37
    • 1
    多克隆
    标记
    • 23
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This STRADB antibody is un-conjugated
    应用范围
    • 28
    • 18
    • 7
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB)
    纯化方法
    This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
    免疫原
    This ALS2CR2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 274-303 amino acids from the C-terminal region of human ALS2CR2.
    克隆位点
    RB15723
    亚型
    Ig Fraction
    Top Product
    Discover our top product STRADB Primary Antibody
  • 应用备注
    WB: 1:1000
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
    有效期
    6 months
  • 抗原
    STRADB (STE20-Related Kinase Adaptor beta (STRADB))
    别名
    ALS2CR2 (STRADB 产品)
    背景
    ALS2CR2 potentiates the antiapoptotic activity of XIAP by enhancing XIAP-mediated activation of JNK1 (MAPK8) and other JNK family members, but not by modulating XIAP-mediated caspase inhibition. Expression of a catalytically inactive TAK1 (MAP3K7) mutant blocks the XIAP/ALS2CR2 activation of JNK1. In vivo coprecipitation experiments show that both ALS2CR2 and XIAP interact with TAK1 and TRAF6. It has been proposed that XIAP-mediated protection from apoptosis utilizes both a JNK1 activation pathway that involves ALS2CR2 and a caspase inhibition pathway that is independent of ALS2CR2.
    分子量
    47026
    基因ID
    55437
    NCBI登录号
    NP_001193793, NP_061041
    UniProt
    Q9C0K7
    途径
    AMPK Signaling
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