PNCK 抗体 (C-Term)
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- 抗原 See all PNCK 抗体
- PNCK (Pregnancy Up-Regulated Non-Ubiquitously Expressed CaM Kinase (PNCK))
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抗原表位
- AA 314-343, C-Term
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This PNCK antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- 纯化方法
- This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
- 免疫原
- This PNCK antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 314-343 amino acids from the C-terminal region of human PNCK.
- 克隆位点
- RB1253-1254
- 亚型
- Ig Fraction
- Top Product
- Discover our top product PNCK Primary Antibody
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- 应用备注
- WB: 1:1000. IHC-P: 1:10~50
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 储存方法
- Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
- 有效期
- 6 months
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Pnck induces ligand-independent EGFR degradation by probable perturbation of the Hsp90 chaperone complex." in: American journal of physiology. Cell physiology, Vol. 300, Issue 5, pp. C1139-54, (2011) (PubMed).
: "Pregnancy-upregulated nonubiquitous calmodulin kinase induces ligand-independent EGFR degradation." in: American journal of physiology. Cell physiology, Vol. 295, Issue 2, pp. C365-77, (2008) (PubMed).
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Pnck induces ligand-independent EGFR degradation by probable perturbation of the Hsp90 chaperone complex." in: American journal of physiology. Cell physiology, Vol. 300, Issue 5, pp. C1139-54, (2011) (PubMed).
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- 抗原
- PNCK (Pregnancy Up-Regulated Non-Ubiquitously Expressed CaM Kinase (PNCK))
- 别名
- PNCK (PNCK 产品)
- 别名
- BSTK3 antibody, CaMK1b antibody, Bstk3 antibody, CaMKIbeta2 antibody, CaMKlb2 antibody, Camk1b antibody, Punc antibody, caMKlb1 antibody, pregnancy up-regulated nonubiquitous CaM kinase antibody, pregnancy upregulated non-ubiquitously expressed CaM kinase antibody, PNCK antibody, Pnck antibody
- 背景
- Protein kinases are enzymes that transfer a phosphate group from a phosphate donor, generally the g phosphate of ATP, onto an acceptor amino acid in a substrate protein. By this basic mechanism, protein kinases mediate most of the signal transduction in eukaryotic cells, regulating cellular metabolism, transcription, cell cycle progression, cytoskeletal rearrangement and cell movement, apoptosis, and differentiation. With more than 500 gene products, the protein kinase family is one of the largest families of proteins in eukaryotes. The family has been classified in 8 major groups based on sequence comparison of their tyrosine (PTK) or serine/threonine (STK) kinase catalytic domains.
- 分子量
- 38500
- 基因ID
- 139728
- NCBI登录号
- NP_001034671, NP_001129212
- UniProt
- Q6P2M8
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