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PGK1 抗体 (AA 117-145)

PGK1 适用: 人 WB, IHC (p), IF, FACS 宿主: 兔 Polyclonal RB05463 unconjugated
产品编号 ABIN391135
发货至: 中国
  • 抗原 See all PGK1 抗体
    PGK1 (Phosphoglycerate Kinase 1 (PGK1))
    抗原表位
    • 7
    • 7
    • 5
    • 5
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 117-145
    适用
    • 71
    • 40
    • 22
    • 5
    • 5
    • 4
    • 4
    • 4
    • 4
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    宿主
    • 63
    • 10
    • 1
    • 1
    克隆类型
    • 57
    • 15
    多克隆
    标记
    • 46
    • 6
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    This PGK1 antibody is un-conjugated
    应用范围
    • 56
    • 33
    • 30
    • 14
    • 12
    • 10
    • 6
    • 5
    • 4
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF), Flow Cytometry (FACS)
    预测反应
    Hs, Pr, M, Rat
    纯化方法
    This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
    免疫原
    This PGK1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 117-145 amino acids from the Central region of human PGK1.
    克隆位点
    RB05463
    亚型
    Ig Fraction
    Top Product
    Discover our top product PGK1 Primary Antibody
  • 应用备注
    IF: 1:10~50. WB: 1:1000. IHC-P: 1:10~50. IHC-P: 1:100. FC: 1:10~50
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
    有效期
    6 months
  • Chen, Liu, Wu, Sheu: "Antrodia cinnamomea Inhibits Migration in Human Hepatocellular Carcinoma Cells: The Role of ERp57 and PGK-1." in: The American journal of Chinese medicine, Vol. 43, Issue 8, pp. 1671-96, (2016) (PubMed).

    Ho, Morrison, Silva, Coomber: "The effect of 3-bromopyruvate on human colorectal cancer cells is dependent on glucose concentration but not hexokinase II expression." in: Bioscience reports, Vol. 36, Issue 1, pp. e00299, (2016) (PubMed).

    Xu, Fang, Zhu, Dai, Nie, Chen, Qin, Wang, Wang, Qiao: "Cigarette smoking exposure alters pebp1 DNA methylation and protein profile involved in MAPK signaling pathway in mice testis." in: Biology of reproduction, Vol. 89, Issue 6, pp. 142, (2013) (PubMed).

    Danshina, Geyer, Dai, Goulding, Willis, Kitto, McCarrey, Eddy, OBrien: "Phosphoglycerate kinase 2 (PGK2) is essential for sperm function and male fertility in mice." in: Biology of reproduction, Vol. 82, Issue 1, pp. 136-45, (2009) (PubMed).

    Doran, OConnell, Gannon, Kavanagh, Ohlendieck: "Opposite pathobiochemical fate of pyruvate kinase and adenylate kinase in aged rat skeletal muscle as revealed by proteomic DIGE analysis." in: Proteomics, Vol. 8, Issue 2, pp. 364-77, (2008) (PubMed).

    Kilic, Kasperczyk, Fulda, Debatin: "Role of hypoxia inducible factor-1 alpha in modulation of apoptosis resistance." in: Oncogene, Vol. 26, Issue 14, pp. 2027-38, (2007) (PubMed).

    OConnell, Gannon, Doran, Ohlendieck: "Proteomic profiling reveals a severely perturbed protein expression pattern in aged skeletal muscle." in: International journal of molecular medicine, Vol. 20, Issue 2, pp. 145-53, (2007) (PubMed).

    West, Moore, Biskup, Bugayenko, Smith, Ross, Dawson, Dawson: "Parkinson's disease-associated mutations in leucine-rich repeat kinase 2 augment kinase activity." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 102, Issue 46, pp. 16842-7, (2005) (PubMed).

  • 抗原
    PGK1 (Phosphoglycerate Kinase 1 (PGK1))
    别名
    PGK1 (PGK1 产品)
    别名
    MIG10 antibody, PGKA antibody, Pgk-1 antibody, Pgk antibody, PGK antibody, wu:fd59b07 antibody, wu:fj36g06 antibody, zgc:56252 antibody, zgc:77899 antibody, PGK1 antibody, phosphoglycerate kinase 1 antibody, pgk2 antibody, pgka antibody, phosphoglycerate kinase 1 antibody, phosphoglycerate kinase 1 L homeolog antibody, PGK1 antibody, Pgk1 antibody, pgk1 antibody, LOC100348124 antibody, pgk1.L antibody
    背景
    Also known as ATP:3-phosphoglycerate 1-phosphotransferase (EC 2.7.2.3), this major enzyme in glycolysis catalyzes the reversible conversion of 1,3-diphosphoglycerate to 3-phosphoglycerate, generating one molecule of ATP. New blood vessel formation or angiogenesis is critical for tumor expansion and metastasis. Lay et al. (2000) showed that the plasmin reductase isolated from conditioned medium of fibrosarcoma cells is the glycolytic enzyme phosphoglycerate kinase. They concluded that phosphoglycerate kinase not only functions in glycolysis but is secreted by tumor cells and participates in the angiogenic process as a disulfide reductase.
    分子量
    44615
    基因ID
    5230
    NCBI登录号
    NP_000282
    UniProt
    P00558
    途径
    Cellular Glucan Metabolic Process
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