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ADK 抗体 (C-Term)

ADK 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal RB05395 unconjugated
产品编号 ABIN391132
发货至: 中国
  • 抗原 See all ADK 抗体
    ADK (Adenosine Kinase (ADK))
    抗原表位
    • 7
    • 7
    • 6
    • 6
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 322-352, C-Term
    适用
    • 50
    • 27
    • 11
    宿主
    • 44
    • 8
    克隆类型
    • 45
    • 6
    多克隆
    标记
    • 31
    • 4
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This ADK antibody is un-conjugated
    应用范围
    • 40
    • 28
    • 14
    • 10
    • 6
    • 5
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    纯化方法
    This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
    免疫原
    This ADK antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 322-352 amino acids from the C-terminal region of human ADK.
    克隆位点
    RB05395
    亚型
    Ig Fraction
    Top Product
    Discover our top product ADK Primary Antibody
  • 应用备注
    WB: 1:1000. IHC-P: 1:10~50
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
    有效期
    6 months
  • Annes, Ryu, Lam, Carolan, Utz, Hollister-Lock, Arvanites, Rubin, Weir, Melton: "Adenosine kinase inhibition selectively promotes rodent and porcine islet ?-cell replication." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 109, Issue 10, pp. 3915-20, (2012) (PubMed).

  • 抗原
    ADK (Adenosine Kinase (ADK))
    别名
    ADK (ADK 产品)
    别名
    AK antibody, ADK antibody, DDBDRAFT_0186795 antibody, DDBDRAFT_0230174 antibody, DDB_0186795 antibody, DDB_0230174 antibody, ATPADK1 antibody, F3G5.4 antibody, F3G5_4 antibody, adenosine kinase antibody, adk antibody, 2310026J05Rik antibody, 5033405D03Rik antibody, AI255373 antibody, AI987814 antibody, Ak antibody, adenosine kinase antibody, ATP:adenosine 5'-phosphotransferase antibody, Adenosine kinase antibody, adenosine kinase S homeolog antibody, ADK antibody, adk antibody, Adk antibody, CNN02130 antibody, LOC5572668 antibody, CMU_026370 antibody, adk.S antibody
    背景
    Adenosine kinase is an abundant enzyme in mammalian tissues. The enzyme catalyzes the transfer of the gamma-phosphate from ATP to adenosine, thereby serving as a regulator of concentrations of both extracellular adenosine and intracellular adenine nucleotides. Adenosine has widespread effects on the cardiovascular, nervous, respiratory, and immune systems and inhibitors of the enzyme could play an important pharmacological role in increasing intravascular adenosine concentrations and acting as anti-inflammatory agents. Alternative splicing results in two transcript variants encoding different isoforms. Both isoforms of the enzyme phosphorylate adenosine with identical kinetics and both require Mg2+ for activity.
    分子量
    40545
    基因ID
    132
    NCBI登录号
    NP_001114, NP_001189378, NP_001189379, NP_006712
    UniProt
    P55263
    途径
    Ribonucleoside Biosynthetic Process
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