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ADK 抗体 (N-Term)

ADK 适用: 人, 小鼠 WB 宿主: 兔 Polyclonal RB05253-05254 unconjugated
产品编号 ABIN391131
发货至: 中国
  • 抗原 See all ADK 抗体
    ADK (Adenosine Kinase (ADK))
    抗原表位
    • 7
    • 6
    • 6
    • 6
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 35-65, N-Term
    适用
    • 50
    • 26
    • 11
    人, 小鼠
    宿主
    • 44
    • 8
    克隆类型
    • 45
    • 6
    多克隆
    标记
    • 31
    • 4
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This ADK antibody is un-conjugated
    应用范围
    • 40
    • 28
    • 14
    • 10
    • 7
    • 5
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB)
    预测反应
    Rat
    纯化方法
    This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
    免疫原
    This ADK antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 35-65 amino acids from the N-terminal region of human ADK.
    克隆位点
    RB05253-05254
    亚型
    Ig Fraction
    Top Product
    Discover our top product ADK Primary Antibody
  • 应用备注
    WB: 1:1000
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
    有效期
    6 months
  • 抗原
    ADK (Adenosine Kinase (ADK))
    别名
    ADK (ADK 产品)
    别名
    AK antibody, ADK antibody, DDBDRAFT_0186795 antibody, DDBDRAFT_0230174 antibody, DDB_0186795 antibody, DDB_0230174 antibody, ATPADK1 antibody, F3G5.4 antibody, F3G5_4 antibody, adenosine kinase antibody, adk antibody, 2310026J05Rik antibody, 5033405D03Rik antibody, AI255373 antibody, AI987814 antibody, Ak antibody, adenosine kinase antibody, ATP:adenosine 5'-phosphotransferase antibody, Adenosine kinase antibody, adenosine kinase S homeolog antibody, ADK antibody, adk antibody, Adk antibody, CNN02130 antibody, LOC5572668 antibody, CMU_026370 antibody, adk.S antibody
    背景
    Adenosine kinase (ATP:adenosine 5-prime-phosphotransferase) is an abundant enzyme in mammalian tissues that catalyzes the transfer of the gamma-phosphate from ATP to adenosine, thereby serving as a potentially important regulator of concentrations of both extracellular adenosine and intracellular adenine nucleotides. Adenosine has widespread effects on the cardiovascular, nervous, respiratory, and immune systems and inhibitors of ADK could play an important pharmacological role in increasing intravascular adenosine concentrations and acting as antiinflammatory agents. The encoded protein does not present any sequence similarities to other well-characterized mammalian nucleoside kinases. In contrast, 2 regions were identified with significant sequence identity to microbial ribokinase and fructokinases and a bacterial inosine/guanosine kinase. Thus, ADK is a structurally distinct mammalian nucleoside kinase that appears to be akin to sugar kinases of microbial origin. Animal studies have demonstrated that a deficiency of adenosine metabolism a powerful contributor to the development of neonatal hepatic steatosis, providing a model for the rapid development of postnatally lethal fatty liver.
    分子量
    40545
    基因ID
    132
    NCBI登录号
    NP_001114, NP_001189378, NP_001189379, NP_006712
    UniProt
    P55263
    途径
    Ribonucleoside Biosynthetic Process
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