ADK 抗体 (N-Term)
Quick Overview for ADK 抗体 (N-Term) (ABIN391131)
抗原
See all ADK 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 35-65, N-Term
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预测反应
- Rat
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纯化方法
- This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
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免疫原
- This ADK antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 35-65 amino acids from the N-terminal region of human ADK.
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亚型
- Ig Fraction
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anti-Adenosine Kinase (ADK) (AA 1-361) antibody
ADK 适用: 小鼠 WB, IHC, ICC, IP 宿主: 兔 Polyclonal unconjugated
anti-Adenosine Kinase (ADK) antibodyADK 适用: 小鼠, 大鼠 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Adenosine Kinase (ADK) (AA 200-345) antibodyADK 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Adenosine Kinase (ADK) antibodyKO Validated ADK 适用: 人 WB, IF, ICC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Adenosine Kinase (ADK) (AA 18-256) antibodyADK 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Adenosine Kinase (ADK) antibodyADK 适用: 人, 小鼠, 大鼠 WB, IHC (p), FACS 宿主: 兔 Polyclonal unconjugated
anti-Adenosine Kinase (ADK) (AA 1-345) antibodyADK 适用: 人 WB, IHC (p) 宿主: 小鼠 Monoclonal 1103CT3-4-3 unconjugated
anti-Adenosine Kinase (ADK) (AA 236-345) antibodyADK 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-Adenosine Kinase (ADK) (AA 236-345) antibodyADK 适用: 人 ELISA 宿主: 小鼠 Monoclonal 4E7 unconjugated
anti-Adenosine Kinase (ADK) (N-Term) antibodyADK 适用: 人, 小鼠, 大鼠 WB, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
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应用备注
- WB: 1:1000
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
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有效期
- 6 months
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- ADK (Adenosine Kinase (ADK))
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别名
- ADK
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背景
- Adenosine kinase (ATP:adenosine 5-prime-phosphotransferase) is an abundant enzyme in mammalian tissues that catalyzes the transfer of the gamma-phosphate from ATP to adenosine, thereby serving as a potentially important regulator of concentrations of both extracellular adenosine and intracellular adenine nucleotides. Adenosine has widespread effects on the cardiovascular, nervous, respiratory, and immune systems and inhibitors of ADK could play an important pharmacological role in increasing intravascular adenosine concentrations and acting as antiinflammatory agents. The encoded protein does not present any sequence similarities to other well-characterized mammalian nucleoside kinases. In contrast, 2 regions were identified with significant sequence identity to microbial ribokinase and fructokinases and a bacterial inosine/guanosine kinase. Thus, ADK is a structurally distinct mammalian nucleoside kinase that appears to be akin to sugar kinases of microbial origin. Animal studies have demonstrated that a deficiency of adenosine metabolism a powerful contributor to the development of neonatal hepatic steatosis, providing a model for the rapid development of postnatally lethal fatty liver.
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分子量
- 40545
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基因ID
- 132
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NCBI登录号
- NP_001114, NP_001189378, NP_001189379, NP_006712
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UniProt
- P55263
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途径
- Ribonucleoside Biosynthetic Process
抗原
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