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Ketohexokinase 抗体 (C-Term)

KHK 适用: 人, 小鼠 WB 宿主: 兔 Polyclonal RB05412 unconjugated
产品编号 ABIN391089
发货至: 中国
  • 抗原 See all Ketohexokinase (KHK) 抗体
    Ketohexokinase (KHK)
    抗原表位
    • 15
    • 13
    • 8
    • 7
    • 4
    • 3
    • 1
    • 1
    • 1
    • 1
    AA 251-281, C-Term
    适用
    • 67
    • 32
    • 6
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    人, 小鼠
    宿主
    • 60
    • 6
    • 1
    克隆类型
    • 62
    • 5
    多克隆
    标记
    • 31
    • 5
    • 4
    • 3
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This Ketohexokinase antibody is un-conjugated
    应用范围
    • 54
    • 27
    • 13
    • 13
    • 13
    • 7
    • 7
    • 6
    • 4
    • 3
    • 3
    • 3
    • 2
    • 1
    Western Blotting (WB)
    纯化方法
    This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
    免疫原
    This Ketohexokinase (KHK) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 251-281 amino acids from the C-terminal region of human Ketohexokinase (KHK).
    克隆位点
    RB05412
    亚型
    Ig Fraction
    Top Product
    Discover our top product KHK Primary Antibody
  • 应用备注
    WB: 1:1000. WB: 1:1000
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
    有效期
    6 months
  • Springer, Lindbloom-Hawley, Schermerhorn: "Tissue expression of ketohexokinase in cats." in: Research in veterinary science, Vol. 87, Issue 1, pp. 115-7, (2009) (PubMed).

    Diggle, Shires, Leitch, Brooke, Carr, Markham, Hayward, Asipu, Bonthron: "Ketohexokinase: expression and localization of the principal fructose-metabolizing enzyme." in: The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society, Vol. 57, Issue 8, pp. 763-74, (2009) (PubMed).

  • 抗原
    Ketohexokinase (KHK)
    Abstract
    KHK 产品
    别名
    wu:fj68h03 antibody, zgc:92219 antibody, zgc:92626 antibody, KHK antibody, khk antibody, KETHPRO antibody, ketohexokinase antibody, Ketohexokinase antibody, KHK antibody, khk antibody, Hhal_0921 antibody, AaeL_AAEL006316 antibody, Nwat_0240 antibody, Khk antibody
    背景
    Ketohexokinase (KHK), or fructokinase, catalyzes conversion of fructose to fructose-1-phosphate. Splice variant 1 is the highly active form found in liver, renal cortex, and small intestine, while splice variant 2 is the lower activity form found in most other tissues. KHK, like glucokinase (GCK) and glucokinase regulator (GCKR), is present in both liver and pancreatic islets. The inhibition of GCK by GCKR is blocked by binding of fructose-1-phosphate to GCKR. The chromosomal proximity of the metabolically connected GCKR and KHK genes has a genetic linkage in type 2 diabetes. Fructosuria, or hepatic fructokinase deficiency, is a benign, asymptomatic defect of intermediary metabolism associated with heterozygosity for G50R and A43T mutations in KHK.
    分子量
    32523
    基因ID
    3795
    NCBI登录号
    NP_000212, NP_006479
    UniProt
    P50053
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