PRKD3 抗体 (AA 352-384)
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- 抗原 See all PRKD3 抗体
- PRKD3 (Protein Kinase D3 (PRKD3))
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抗原表位
- AA 352-384
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This PRKD3 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- 纯化方法
- This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
- 免疫原
- This PKC-nu antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 352-384 amino acids from human PKC-nu.
- 克隆位点
- RB1047
- 亚型
- Ig Fraction
- Top Product
- Discover our top product PRKD3 Primary Antibody
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- 应用备注
- WB: 1:1000. WB: 1:1000. IHC-P: 1:50~100
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 储存方法
- Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
- 有效期
- 6 months
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Protein kinase D3 (PKD3) contributes to prostate cancer cell growth and survival through a PKCepsilon/PKD3 pathway downstream of Akt and ERK 1/2." in: Cancer research, Vol. 68, Issue 10, pp. 3844-53, (2008) (PubMed).
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Protein kinase D3 (PKD3) contributes to prostate cancer cell growth and survival through a PKCepsilon/PKD3 pathway downstream of Akt and ERK 1/2." in: Cancer research, Vol. 68, Issue 10, pp. 3844-53, (2008) (PubMed).
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- 抗原
- PRKD3 (Protein Kinase D3 (PRKD3))
- 别名
- PKC nu (PRKD3 产品)
- 别名
- EPK2 antibody, PKC-NU antibody, PKD3 antibody, PRKCN antibody, nPKC-NU antibody, PRKD3 antibody, 4930557O20Rik antibody, 5730497N19Rik antibody, Pkcnu antibody, Prkcn antibody, protein kinase D3 antibody, PRKD3 antibody, prkd3 antibody, Prkd3 antibody
- 背景
- Protein kinase C (PKC) is a family of serine- and threonine-specific protein kinases that can be activated by calcium and second messenger diacylglycerol. PKC family members phosphorylate a wide variety of protein targets and are known to be involved in diverse cellular signaling pathways. PKC also serve as major receptors for phorbol esters, a class of tumor promoters. Each member of the PKC family has a specific expression profile and is believed to play distinct roles in cells. PKC nu is one of the PKC family members. This kinase can be activated rapidly by the agonists of G protein-coupled receptors. It resides in both cytoplasm and nucleus, and its nuclear accumulation is found to be dramatically enhanced in response to its activation. This kinase can also be activated after B-cell antigen receptor (BCR) engagement, which requires intact phopholipase C gamma and the involvement of other PKC family members.
- 分子量
- 100471
- 基因ID
- 23683
- NCBI登录号
- NP_005804
- UniProt
- O94806
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