PKC alpha 抗体 (C-Term)
-
- 抗原 See all PKC alpha (PKCa) 抗体
- PKC alpha (PKCa) (Protein Kinase C, alpha (PKCa))
-
抗原表位
- AA 299-329, C-Term
-
适用
- 人
-
宿主
- 兔
-
克隆类型
- 多克隆
-
标记
- This PKC alpha antibody is un-conjugated
-
应用范围
- Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Flow Cytometry (FACS), Immunofluorescence (IF)
- 预测反应
- M, Rb, Rat
- 纯化方法
- This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
- 免疫原
- This PKC alpha antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 299-329 amino acids from the C-terminal region of human PKC alpha.
- 克隆位点
- RB01012
- 亚型
- Ig Fraction
- Top Product
- Discover our top product PKCa Primary Antibody
-
-
- 应用备注
- IF: 1:10~50. WB: 1:1000. IHC-P: 1:10~50. FC: 1:10~50
- 限制
- 仅限研究用
-
- 状态
- Liquid
- 缓冲液
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 储存方法
- Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
- 有效期
- 6 months
-
-
Phospholipase D regulates myogenic differentiation through the activation of both mTORC1 and mTORC2 complexes." in: The Journal of biological chemistry, Vol. 286, Issue 25, pp. 22609-21, (2011) (PubMed).
: "
-
Phospholipase D regulates myogenic differentiation through the activation of both mTORC1 and mTORC2 complexes." in: The Journal of biological chemistry, Vol. 286, Issue 25, pp. 22609-21, (2011) (PubMed).
-
- 抗原
- PKC alpha (PKCa) (Protein Kinase C, alpha (PKCa))
- 别名
- PKC alpha (PKCa 产品)
- 别名
- pkc-alpha antibody, pkcalpha antibody, im:7139045 antibody, si:dkey-8l19.1 antibody, LOC100219195 antibody, AAG6 antibody, PKC-alpha antibody, PKCA antibody, PRKACA antibody, AI875142 antibody, Pkca antibody, PKRCA antibody, protein kinase C alpha antibody, protein kinase C, alpha L homeolog antibody, protein kinase C, alpha antibody, PRKCA antibody, prkca.L antibody, prkca antibody, Prkca antibody
- 背景
- Protein kinase C (PKC) is a family of serine- and threonine-specific protein kinases that can be activated by calcium and the second messenger diacylglycerol. PKC family members phosphorylate a wide variety of protein targets and are known to be involved in diverse cellular signaling pathways. PKC family members also serve as major receptors for phorbol esters, a class of tumor promoters. Each member of the PKC family has a specific expression profile and is believed to play a distinct role in cells. PKC alpha is one of the PKC family members. This kinase has been reported to play roles in many different cellular processes, such as cell adhesion, cell transformation, cell cycle checkpoint, and cell volume control. Knockout studies in mice suggest that this kinase may be a fundamental regulator of cardiac contractility and Ca(2+) handling in myocytes.
- 分子量
- 76750
- 基因ID
- 5578
- NCBI登录号
- NP_002728
- UniProt
- P17252
- 途径
- WNT signaling, TCR Signaling, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Thyroid Hormone Synthesis, cAMP Metabolic Process, Myometrial Relaxation and Contraction, Cell-Cell Junction Organization, Regulation of G-Protein Coupled Receptor Protein Signaling, G-protein mediated Events, Signaling Events mediated by VEGFR1 and VEGFR2, Interaction of EGFR with phospholipase C-gamma, Thromboxane A2 Receptor Signaling, VEGFR1 Specific Signals, VEGF Signaling
-