This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
免疫原
This RGP1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 243-271 amino acids from the C-terminal region of human RGP1.
Retrograde golgi transport homolog 1 (RGP1) is the mammalian homolog to the yeast RGP1, and is thought to be a potential Golgi recycling factor. The protein forms a tight complex with RIC1 and this complex binds Ypt6p and stimulates guanine nucleotide exchange. RGP1 yeast mutants exhibit defects in retrograde trafficking that are similar to those seen in yeast, with mutations in other retrograde Golgi transport proteins. It is expected that RGP1 plays a similar role in mammalian cells.