MTMR4 抗体 (C-Term)
(3 references)-
- 抗原 See all MTMR4 抗体
- MTMR4 (Myotubularin Related Protein 4 (MTMR4))
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抗原表位
- AA 1155-1187, C-Term
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适用
- 人, 小鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This MTMR4 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- 纯化方法
- This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
- 免疫原
- This MTMR4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1155-1187 amino acids from the C-terminal region of human MTMR4.
- 克隆位点
- RB0716
- 亚型
- Ig Fraction
- Top Product
- Discover our top product MTMR4 Primary Antibody
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anti-Myotubularin Related Protein 4 (MTMR4) (AA 920-1195) antibody
MTMR4 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Myotubularin Related Protein 4 (MTMR4) (AA 570-820) antibodyMTMR4 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Myotubularin Related Protein 4 (MTMR4) antibodyMTMR4 适用: 人, 小鼠 IF 宿主: 兔 Polyclonal unconjugated
anti-Myotubularin Related Protein 4 (MTMR4) (AA 1-1195) antibodyMTMR4 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
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- 应用备注
- WB: 1:1000. IHC-P: 1:10~50
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 储存方法
- Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
- 有效期
- 6 months
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: "Myotubularin-related protein 4 (MTMR4) attenuates BMP/Dpp signaling by dephosphorylation of Smad proteins." in: The Journal of biological chemistry, Vol. 288, Issue 1, pp. 79-88, (2013) (PubMed).
: "MTMR4 attenuates transforming growth factor beta (TGFbeta) signaling by dephosphorylating R-Smads in endosomes." in: The Journal of biological chemistry, Vol. 285, Issue 11, pp. 8454-62, (2010) (PubMed).
: "The inositol phosphatase MTMR4 is a novel target of the ubiquitin ligase Nedd4." in: The Biochemical journal, Vol. 419, Issue 1, pp. 57-63, (2009) (PubMed).
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: "Myotubularin-related protein 4 (MTMR4) attenuates BMP/Dpp signaling by dephosphorylation of Smad proteins." in: The Journal of biological chemistry, Vol. 288, Issue 1, pp. 79-88, (2013) (PubMed).
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- 抗原
- MTMR4 (Myotubularin Related Protein 4 (MTMR4))
- 别名
- MTMR4 (MTMR4 产品)
- 别名
- zfyve11 antibody, fyve-dsp2 antibody, FYVE-DSP2 antibody, ZFYVE11 antibody, AA596759 antibody, ESTM44 antibody, mKIAA0647 antibody, myotubularin related protein 4 antibody, myotubularin related protein 4 L homeolog antibody, Mtmr4 antibody, MTMR4 antibody, mtmr4 antibody, mtmr4.L antibody
- 背景
- MTMR, a member of the myotubularin family, encodes an intracellular protein of 1,195 amino acids, and shares approximately 47 % sequence identity with MTMR3, spiking to over 70 % identity in the catalytic domain and the double zinc finger (FYVE) motif. PCR analysis detects expression of MTMR4 in all human tissues examined except lung, small intestine, stomach, salivary gland, adrenal gland, and uterus. Subcellular localization of MTMR4 in transfected HeLa cells showed a perinuclear distribution, similar to that seen with MTMR3. MTMR4 dephosphorylates para-nitrophenylphosphate and phosphatidylinositol 3-phosphate.
- 分子量
- 133353
- 基因ID
- 9110
- NCBI登录号
- NP_004678
- UniProt
- Q9NYA4
- 途径
- Inositol Metabolic Process
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