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CCL2 抗体 (C-Term)

Name: CCL2 抗体 (C-Term)
SKU: ABIN390653
Availability: OutOfStock

CCL2 适用: 人 WB, IHC (p), IF, FACS 宿主: 兔 Polyclonal RB17838 unconjugated

Western blot analysis of CCL2 Antibody (C-term) (ABIN390653 and ABIN2840951) in Hela cell line lysates (35 μg/lane). (CCL2 抗体 (C-Term))

Formalin-fixed and paraffin-embedded human brain tissue with CCL2 Antibody (C-term), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. (CCL2 抗体 (C-Term))

IHC (p)

Immunofluorescence analysis of CCL2 Antibody (C-term) with hela cells. (CCL2 抗体 (C-Term))

Confocal immunofluorescent analysis of CCL2 Antibody (C-term) (ABIN390653 and ABIN2840951) with Hela cell followed by Alexa Fluor 488-conjugated goat anti-rabbit lgG (green). (CCL2 抗体 (C-Term))

Flow cytometric analysis of hela cells using CCL2 Antibody (C-term)(bottom histogram) compared to a negative control cell (top histogram). (CCL2 抗体 (C-Term))

FACS

5 images

(1 reference)

产品编号 ABIN390653

发货至: 中国

Datasheet as PDF

抗原 See all CCL2 抗体

CCL2 (Chemokine (C-C Motif) Ligand 2 (CCL2))
抗原表位
22

15

13

10

8

4

3

3

3

2

2

2

2

1

1

1

1

1

1
AA 62-89, C-Term
适用
111

69

63

18

18

18

16

8

3

3

2

1

1
人
宿主
128

57

8

7

5

3

2
兔
Compatible Secondaries
克隆类型
144

66
多克隆
标记
110

31

17

6

4

3

3

3

3

3

3

2

2

2

2

2

2

2

2

2

2

2

1

1

1
This CCL2 antibody is un-conjugated
应用范围
143

73

60

26

26

25

24

18

15

15

13

13

13

11

11

6

3

2

1

1
Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF), Flow Cytometry (FACS)

预测反应

Pr

纯化方法

This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

免疫原

This CCL2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 62-89 amino acids from the C-terminal region of human CCL2.

克隆位点

RB17838

亚型

Ig Fraction

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anti-Chemokine (C-C Motif) Ligand 2 (CCL2) (AA 24-99) antibody
CCL2 适用: 人 WB, IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated

anti-Chemokine (C-C Motif) Ligand 2 (CCL2) antibody
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anti-Chemokine (C-C Motif) Ligand 2 (CCL2) (AA 24-99) antibody
CCL2 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated

应用备注

IF: 1:10~50. IF: 1:10~50. WB: 1:1000. IHC-P: 1:10~50. FC: 1:10~50

限制

仅限研究用
状态

Liquid

缓冲液

Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

储存液

Sodium azide

注意事项

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

储存条件

4 °C,-20 °C

储存方法

Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

有效期

6 months
Bannon, Johnson, Michelhaugh, Hartley, Halter, David, Kapatos, Schmidt: "A molecular profile of cocaine abuse includes the differential expression of genes that regulate transcription, chromatin, and dopamine cell phenotype." in: Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, Vol. 39, Issue 9, pp. 2191-9, (2014) (PubMed).
抗原

CCL2 (Chemokine (C-C Motif) Ligand 2 (CCL2))

别名

CCL2 (CCL2 产品)

别名

GDCF-2 antibody, HC11 antibody, HSMCR30 antibody, MCAF antibody, MCP-1 antibody, MCP1 antibody, SCYA2 antibody, SMC-CF antibody, AI323594 antibody, JE antibody, Scya2 antibody, Sigje antibody, MCP-1A antibody, MCP1A antibody, C-C motif chemokine ligand 2 antibody, chemokine (C-C motif) ligand 2 antibody, C-C motif chemokine 2 antibody, CCL2 antibody, Ccl2 antibody, LOC101120093 antibody

背景

Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. CCL2 is structurally related to the CXC subfamily of cytokines. Members of this subfamily are characterized by two cysteines separated by a single amino acid. This cytokine displays chemotactic activity for monocytes and basophils but not for neutrophils or eosinophils. It has been implicated in the pathogenesis of diseases characterized by monocytic infiltrates, like psoriasis, rheumatoid arthritis and atherosclerosis. It binds to chemokine receptors CCR2 and CCR4.

分子量

11025

基因ID

6347

NCBI登录号

NP_002973

UniProt

P13500

途径

Cellular Response to Molecule of Bacterial Origin, Positive Regulation of Immune Effector Process, ER-Nucleus Signaling, Unfolded Protein Response, The Global Phosphorylation Landscape of SARS-CoV-2 Infection