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TBP 抗体 (AA 210-239)

Name: TBP 抗体 (AA 210-239)
SKU: ABIN390631
Availability: OutOfStock

TBP 适用: 人 WB, IF, IHC (p), FACS 宿主: 兔 Polyclonal RB20259 unconjugated

TBP Antibody (Center) (ABIN390631 and ABIN2840935) western blot analysis in K562, cell line lysates (35 μg/lane). (TBP 抗体 (AA 210-239))

Formalin-fixed and paraffin-embedded human testis tissue reacted with TBP Antibody (Center), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. (TBP 抗体 (AA 210-239))

IHC (p)

Fluorescent confocal image of cell stained with TBP Antibody (Center) (ABIN390631 and ABIN2840935). (TBP 抗体 (AA 210-239))

TBP Antibody (Center) (ABIN390631 and ABIN2840935) flow cytometry analysis of HL-60 cells (bottom histogram) compared to a negative control cell (top histogram). (TBP 抗体 (AA 210-239))

FACS

4 images

产品编号 ABIN390631

发货至: 中国

Datasheet as PDF

抗原 See all TBP 抗体

TBP (TATA Box Binding Protein (TBP))
抗原表位
15

6

5

4

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1
AA 210-239
适用
75

45

43

6

6

5

5

4

4

3

3

3

3

2

2

1

1
人
宿主
57

18

2
兔
Compatible Secondaries
克隆类型
59

18
多克隆
标记
45

3

3

3

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1
This TBP antibody is un-conjugated
应用范围
59

26

14

13

11

10

9

8

6

4

3

2

1

1

1

1

1

1

1
Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Flow Cytometry (FACS)

预测反应

Zf, X, B, C, Pr, M

纯化方法

This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

免疫原

This TBP antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 210-239 amino acids from the Central region of human TBP.

克隆位点

RB20259

亚型

Ig Fraction

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anti-TATA Box Binding Protein (TBP) (AA 210-239) antibody
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anti-TATA Box Binding Protein (TBP) (AA 8-316) antibody
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anti-TATA Box Binding Protein (TBP) (AA 1-55) antibody
TBP 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated

anti-TATA Box Binding Protein (TBP) (N-Term) antibody
TBP 适用: 人, 小鼠, 大鼠 WB, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated

应用备注

IF: 1:10~50. WB: 1:1000. IHC-P: 1:50~100. FC: 1:10~50

限制

仅限研究用
状态

Liquid

缓冲液

Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

储存液

Sodium azide

注意事项

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

储存条件

4 °C,-20 °C

储存方法

Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

有效期

6 months
抗原

TBP (TATA Box Binding Protein (TBP))

别名

TBP (TBP 产品)

别名

GTF2D antibody, GTF2D1 antibody, HDL4 antibody, SCA17 antibody, TFIID antibody, Gtf2d antibody, fd20h06 antibody, si:zc101n13.2 antibody, wu:fd20h06 antibody, zgc:66213 antibody, TBP1 antibody, TBP antibody, tbp antibody, CG9874 antibody, Dmel\\CG9874 antibody, RBP antibody, TBP38 antibody, TFIIDtau antibody, TfIID antibody, dTBP antibody, dTFIID antibody, dTbp antibody, dtbp antibody, gtf2d antibody, gtf2d1 antibody, sca17 antibody, tfiid antibody, tfiidtau antibody, xtbp antibody, tbp-a antibody, tbp-b antibody, TATA-box binding protein antibody, TATA box binding protein antibody, TATA binding protein antibody, TATA-box binding protein L homeolog antibody, TATA-box-binding protein antibody, TATA-box binding protein S homeolog antibody, TBP antibody, Tbp antibody, tbp antibody, tbp.L antibody, tbp.S antibody

背景

Initiation of transcription by RNA polymerase II requires the activities of more than 70 polypeptides. The protein that coordinates these activities is transcription factor IID (TFIID), which binds to the core promoter to position the polymerase properly, serves as the scaffold for assembly of the remainder of the transcription complex, and acts as a channel for regulatory signals. TFIID is composed of the TATA-binding protein (TBP) and a group of evolutionarily conserved proteins known as TBP-associated factors or TAFs. TAFs may participate in basal transcription, serve as coactivators, function in promoter recognition or modify general transcription factors (GTFs) to facilitate complex assembly and transcription initiation. A distinctive feature of TBP is a long string of glutamines in the N-terminal. This region of the protein modulates the DNA binding activity of the C terminus, and modulation of DNA binding affects the rate of transcription complex formation and initiation of transcription. Mutations that expand the number of CAG repeats encoding this polyglutamine tract, and thus increase the length of the polyglutamine string, are associated with spinocerebellar ataxia 17, a neurodegenerative disorder classified as a polyglutamine disease.

分子量

37698

基因ID

6908

NCBI登录号

NP_001165556, NP_003185

UniProt

P20226

途径

WNT signaling