This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
免疫原
This TBRG1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 6-36 amino acids from the N-terminal region of human TBRG1.
TBRG1 acts as a growth inhibitor. It can activate TP53/p53, cause G1 arrest and collaborate with CDKN2A to restrict proliferation, but it does not require either protein to inhibit DNA synthesis. TBRG1 redistributes CDKN2A into the nucleoplasm, and is involved in maintaining chromosomal stability.