Glypican 3 抗体 (N-Term)
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- 抗原 See all Glypican 3 (GPC3) 抗体
- Glypican 3 (GPC3)
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抗原表位
- AA 21-50, N-Term
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适用
- 人, 小鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This Glypican 3 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- 纯化方法
- This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
- 免疫原
- This Glypican 3 (GPC3) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 21-50 amino acids from the N-terminal region of human Glypican 3 (GPC3).
- 克隆位点
- RB05031
- 亚型
- Ig Fraction
- Top Product
- Discover our top product GPC3 Primary Antibody
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- 应用备注
- WB: 1:2000. WB: 1:2000. WB: 1:1000. IHC-P: 1:50~100
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 储存方法
- Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
- 有效期
- 6 months
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Identification of Glypican-3 as a potential metastasis suppressor gene in gastric cancer." in: Oncotarget, Vol. 7, Issue 28, pp. 44406-44416, (2018) (PubMed).
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Identification of Glypican-3 as a potential metastasis suppressor gene in gastric cancer." in: Oncotarget, Vol. 7, Issue 28, pp. 44406-44416, (2018) (PubMed).
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- 抗原
- Glypican 3 (GPC3)
- Abstract
- GPC3 产品
- 别名
- GPC3 antibody, sgb antibody, dgsx antibody, sdys antibody, sgbs antibody, oci-5 antibody, sgbs1 antibody, DGSX antibody, GTR2-2 antibody, MXR7 antibody, OCI-5 antibody, SDYS antibody, SGB antibody, SGBS antibody, SGBS1 antibody, Glypican-3 antibody, glypican 3 antibody, gpc3 antibody, GPC3 antibody, Gpc3 antibody
- 背景
- GPC3 is a cell surface proteoglycan that bears heparan sulfate. This protein may be involved in the suppression/modulation of growth in the predominantly mesodermal tissues and organs, and may play a role in the modulation of IGF2 interactions with its receptor and thereby modulate its function. Members of the glypican-related integral membrane proteoglycan family contain a core protein anchored to the cytoplasmic membrane via a glycosyl phosphatidylinositol (GPI) linkage. These proteins may play a role in the control of cell division, growth regulation, and tumor predisposition. Deletion mutations in GPC3 are the cause of Simpson-Golabi-Behmel syndrome (SGBS), also known as Simpson dysmorphia syndrome (SDYS). SGBS is a condition characterized by pre- and postnatal overgrowth (gigantism) with visceral and skeletal anomalies.
- 分子量
- 65563
- 基因ID
- 2719
- NCBI登录号
- NP_001158089, NP_001158091, NP_004475
- UniProt
- P51654
- 途径
- Glycosaminoglycan Metabolic Process
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