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Glypican 3 抗体 (N-Term)

GPC3 适用: 人, 小鼠 WB, IHC (p) 宿主: 兔 Polyclonal RB05031 unconjugated
产品编号 ABIN390317
发货至: 中国
  • 抗原 See all Glypican 3 (GPC3) 抗体
    Glypican 3 (GPC3)
    抗原表位
    • 20
    • 16
    • 12
    • 7
    • 6
    • 6
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 21-50, N-Term
    适用
    • 143
    • 49
    • 46
    • 4
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    人, 小鼠
    宿主
    • 88
    • 55
    • 1
    克隆类型
    • 74
    • 69
    • 1
    多克隆
    标记
    • 58
    • 12
    • 7
    • 6
    • 6
    • 6
    • 5
    • 5
    • 5
    • 5
    • 5
    • 5
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This Glypican 3 antibody is un-conjugated
    应用范围
    • 82
    • 78
    • 63
    • 45
    • 36
    • 26
    • 17
    • 15
    • 6
    • 2
    • 2
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    纯化方法
    This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
    免疫原
    This Glypican 3 (GPC3) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 21-50 amino acids from the N-terminal region of human Glypican 3 (GPC3).
    克隆位点
    RB05031
    亚型
    Ig Fraction
    Top Product
    Discover our top product GPC3 Primary Antibody
  • 应用备注
    WB: 1:2000. WB: 1:2000. WB: 1:1000. IHC-P: 1:50~100
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
    有效期
    6 months
  • Han, Ma, Zhao, Zhao, Batista, Zhou, Zhou, Yang, Wang, Bi, Xia, Bai, Garkavtsev, Zhang: "Identification of Glypican-3 as a potential metastasis suppressor gene in gastric cancer." in: Oncotarget, Vol. 7, Issue 28, pp. 44406-44416, (2018) (PubMed).

  • 抗原
    Glypican 3 (GPC3)
    Abstract
    GPC3 产品
    别名
    GPC3 antibody, sgb antibody, dgsx antibody, sdys antibody, sgbs antibody, oci-5 antibody, sgbs1 antibody, DGSX antibody, GTR2-2 antibody, MXR7 antibody, OCI-5 antibody, SDYS antibody, SGB antibody, SGBS antibody, SGBS1 antibody, Glypican-3 antibody, glypican 3 antibody, gpc3 antibody, GPC3 antibody, Gpc3 antibody
    背景
    GPC3 is a cell surface proteoglycan that bears heparan sulfate. This protein may be involved in the suppression/modulation of growth in the predominantly mesodermal tissues and organs, and may play a role in the modulation of IGF2 interactions with its receptor and thereby modulate its function. Members of the glypican-related integral membrane proteoglycan family contain a core protein anchored to the cytoplasmic membrane via a glycosyl phosphatidylinositol (GPI) linkage. These proteins may play a role in the control of cell division, growth regulation, and tumor predisposition. Deletion mutations in GPC3 are the cause of Simpson-Golabi-Behmel syndrome (SGBS), also known as Simpson dysmorphia syndrome (SDYS). SGBS is a condition characterized by pre- and postnatal overgrowth (gigantism) with visceral and skeletal anomalies.
    分子量
    65563
    基因ID
    2719
    NCBI登录号
    NP_001158089, NP_001158091, NP_004475
    UniProt
    P51654
    途径
    Glycosaminoglycan Metabolic Process
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