This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
免疫原
This DSCR3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of human DSCR3.
zgc:92243 antibody, DSCR3 antibody, DKFZp469M1432 antibody, MGC116512 antibody, DCRA antibody, DSCRA antibody, AW538125 antibody, Dcra antibody, DSCR3 arrestin fold containing antibody, Down syndrome critical region 3 antibody, down syndrome critical region protein 3 antibody, DSCR3 arrestin fold containing L homeolog antibody, Dscr3 antibody, DSCR3 antibody, dscr3 antibody, CpipJ_CPIJ008672 antibody, PITG_10989 antibody, dscr3.L antibody
背景
The region of chromosome 21 between genes CBR and ERG (CBR-ERG region), which spans 2.5 Mb on 21q22.2, has been defined by analysis of patients with partial trisomy 21. It contributes significantly to the pathogenesis of many characteristics of Down syndrome, including morphological features, hypotonia, and mental retardation. The DSCR3 (Down syndrome critical region gene 3) gene is found in this region and is predictated to contain eight exons. DSCR3 is expressed in most tissues examined.