Claudin 1 抗体 (AA 40-82)
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- 抗原 See all Claudin 1 (CLDN1) 抗体
- Claudin 1 (CLDN1)
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抗原表位
- AA 40-82
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This Claudin 1 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- 纯化方法
- This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
- 免疫原
- This Claudin 1(CLDN1) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 40-82 amino acids from human Claudin 1(CLDN1).
- 克隆位点
- RB13129
- 亚型
- Ig Fraction
- Top Product
- Discover our top product CLDN1 Primary Antibody
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- 应用备注
- WB: 1:1000. IHC-P: 1:10~50
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 储存方法
- Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
- 有效期
- 6 months
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- 抗原
- Claudin 1 (CLDN1)
- Abstract
- CLDN1 产品
- 背景
- Tight junctions represent one mode of cell-to-cell adhesion in epithelial or endothelial cell sheets, forming continuous seals around cells and serving as a physical barrier to prevent solutes and water from passing freely through the paracellular space. These junctions are comprised of sets of continuous networking strands in the outwardly facing cytoplasmic leaflet, with complementary grooves in the inwardly facing extracytoplasmic leaflet. CLDN1, a member of the claudin family, is an integral membrane protein and a component of tight junction strands. Loss of function mutations result in neonatal ichthyosis-sclerosing cholangitis syndrome.
- 分子量
- 22744
- 基因ID
- 9076
- NCBI登录号
- NP_066924
- UniProt
- O95832
- 途径
- Cell-Cell Junction Organization, Hepatitis C
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