Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
预测反应
B, Rat
纯化方法
This antibody is purified through a protein A column, followed by peptide affinity purification.
免疫原
This ABAD antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 199-235 amino acids from the C-terminal region of human ABAD.
Amyloid b-peptide-binding alcohol dehydrogenase (ABAD) is a member of the family of short chain dehydrogenase/reductases, unique among this family, it binds amyloid b-peptide and exhibits enzymatic activity toward a wide variety of substrates including linear alcohols. In an amyloid beta-abundant environment, ABAD appears to trigger cell stress induced by the amyloid peptide.