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APP 抗体 (N-Term)
APP
适用: 小鼠
WB, IHC (p), FACS
宿主: 兔
Polyclonal
RB5012
unconjugated
APP抗体详情
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抗原
See all APP 抗体
APP
(Amyloid beta (A4) Precursor Protein (APP))
抗原表位
All epitopes for APP 抗体
AA 29-61, N-Term
适用
All reactivities for APP 抗体
小鼠
宿主
All hosts for APP 抗体
兔
克隆类型
All clonalities for APP 抗体
多克隆
标记
All conjugates for APP 抗体
This APP antibody is un-conjugated
应用范围
All applications for APP 抗体
Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Flow Cytometry (FACS)
预测反应
Pr
纯化方法
This antibody is purified through a protein A column, followed by peptide affinity purification.
免疫原
This APP antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 29-61 amino acids from the N-terminal region of human APP.
克隆位点
RB5012
亚型
Ig Fraction
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Discover our top product APP Primary Antibody
Alternatives
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使用细节
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应用备注
WB: 1:2000. IHC-P: 1:10~50. FC: 1:10~50
限制
仅限研究用
贮存及处理
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状态
Liquid
缓冲液
Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
储存液
Sodium azide
注意事项
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
储存条件
4 °C,-20 °C
储存方法
Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
有效期
6 months
APP目标详情
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抗原
APP
(Amyloid beta (A4) Precursor Protein (APP))
别名
APP (APP 产品 )
别名
AAA antibody, ABETA antibody, ABPP antibody, AD1 antibody, APPI antibody, CTFgamma antibody, CVAP antibody, PN-II antibody, PN2 antibody, aaa antibody, abeta antibody, abpp antibody, ad1 antibody, appi antibody, ctfgamma antibody, cvap antibody, pn2 antibody, APP antibody, APP-like antibody, APPL antibody, Abeta antibody, BcDNA:GH04413 antibody, CG7727 antibody, Dmel\\CG7727 antibody, EG:65F1.5 antibody, appl antibody, Abpp antibody, Adap antibody, Ag antibody, Cvap antibody, E030013M08Rik antibody, betaApp antibody, app antibody, wu:fj34d10 antibody, wu:fk65e12 antibody, zgc:85740 antibody, amyloid beta precursor protein antibody, amyloid beta (A4) precursor protein antibody, beta amyloid protein precursor-like antibody, amyloid beta (A4) precursor protein a antibody, amyloid beta precursor protein L homeolog antibody, APP antibody, app antibody, Appl antibody, App antibody, appa antibody, app.L antibody
背景
APP is a cell surface receptor and transmembrane precursor protein that is cleaved by secretases to form a number of peptides. Some of these peptides are secreted and can bind to the acetyltransferase complex APBB1/TIP60 to promote transcriptional activation, while others form the protein basis of the amyloid plaques found in the brains of patients with Alzheimer disease. Mutations in this gene have been implicated in autosomal dominant Alzheimer disease and cerebroarterial amyloidosis (cerebral amyloid angiopathy).
分子量
86943
基因ID
351
NCBI登录号
NP_000475 , NP_001129488 , NP_001129601 , NP_001129602 , NP_001129603 , NP_001191230 , NP_001191231 , NP_001191232 , NP_958816 , NP_958817
UniProt
P05067
途径
Caspase Cascade in Apoptosis , EGFR Signaling Pathway , Transition Metal Ion Homeostasis , Skeletal Muscle Fiber Development , Toll-Like Receptors Cascades , Feeding Behaviour
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