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HIRA 抗体 (AA 431-461)

HIRA 适用: 人 WB 宿主: 兔 Polyclonal RB13843 unconjugated
产品编号 ABIN390223
发货至: 中国
  • 抗原 See all HIRA 抗体
    HIRA (HIR Histone Cell Cycle Regulation Defective Homolog A (HIRA))
    抗原表位
    • 15
    • 8
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 431-461
    适用
    • 39
    • 34
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    宿主
    • 46
    • 11
    克隆类型
    • 46
    • 11
    多克隆
    标记
    • 31
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This HIRA antibody is un-conjugated
    应用范围
    • 40
    • 19
    • 13
    • 13
    • 8
    • 7
    • 5
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    Western Blotting (WB)
    预测反应
    C, M, X
    纯化方法
    This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
    免疫原
    This HIRA antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 431-461 amino acids from the Central region of human HIRA.
    克隆位点
    RB13843
    亚型
    Ig Fraction
    Top Product
    Discover our top product HIRA Primary Antibody
  • 应用备注
    WB: 1:1000
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
    有效期
    6 months
  • 抗原
    HIRA (HIR Histone Cell Cycle Regulation Defective Homolog A (HIRA))
    别名
    HIRA (HIRA 产品)
    背景
    HIRA is a histone chaperone that preferentially places the variant histone H3.3 in nucleosomes. Orthologs of this protein in yeast, flies, and plants are necessary for the formation of transcriptionally silent heterochomatin. It plays an important role in the formation of the senescence-associated heterochromatin foci. These foci likely mediate the irreversible cell cycle changes that occur in senescent cells. It is considered the primary candidate protein in some haploinsufficiency syndromes such as DiGeorge syndrome, and insufficient production of the gene may disrupt normal embryonic development.
    分子量
    111835
    基因ID
    7290
    NCBI登录号
    NP_003316
    UniProt
    P54198
    途径
    Chromatin Binding
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