Sclerostin 抗体 (N-Term)
(2 references)-
- 抗原 See all Sclerostin (SOST) 抗体
- Sclerostin (SOST)
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抗原表位
- AA 12-42, N-Term
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适用
- 人, 小鼠, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This Sclerostin antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- 预测反应
- B
- 纯化方法
- This antibody is purified through a protein A column, followed by peptide affinity purification.
- 免疫原
- This SOST antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 12-42 amino acids from the N-terminal region of human SOST.
- 克隆位点
- RB12388
- 亚型
- IgG
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anti-Sclerostin (SOST) (AA 25-213) antibody
SOST 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Sclerostin (SOST) (AA 24-213) antibodySOST 适用: 人 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Sclerostin (SOST) (AA 24-213) antibodySOST 适用: 人 IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Sclerostin (SOST) (AA 121-180) antibodySOST 适用: 人, 小鼠, 大鼠, 兔 WB, ELISA, IF (p), ICC, IHC (p), IF (cc), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Sclerostin (SOST) (N-Term) antibodySOST 适用: 人, 小鼠 WB, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated
anti-Sclerostin (SOST) (AA 25-209) antibodySOST 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Sclerostin (SOST) (AA 38-87) antibodySOST 适用: 人, 犬, Pig, 马, Bat, 猴 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Sclerostin (SOST) (C-Term) antibodyVerified SOST 适用: 人 IHC, ELISA 宿主: 山羊 Polyclonal unconjugated
anti-Sclerostin (SOST) (AA 134-163) antibodySOST 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal RB13011 unconjugated
anti-Sclerostin (SOST) (AA 38-66), (N-Term) antibodySOST 适用: 人, 小鼠 WB 宿主: 兔 Polyclonal RB36187 unconjugated
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- 应用备注
- WB: 1:1000. WB: 1:2000. WB: 1:1000. WB: 1:2000. IHC-P-Leica: 1:500
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid freeze-thaw cycles.
- 储存条件
- 4 °C,-20 °C
- 储存方法
- Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots.
- 有效期
- 6 months
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: "Co-expression of DKK-1 and Sclerostin in Subchondral Bone of the Proximal Femoral Heads from Osteoarthritic Hips." in: Calcified tissue international, Vol. 100, Issue 6, pp. 609-618, (2018) (PubMed).
: "Single-pulsed electromagnetic field therapy increases osteogenic differentiation through Wnt signaling pathway and sclerostin downregulation." in: Bioelectromagnetics, Vol. 36, Issue 7, pp. 494-505, (2015) (PubMed).
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: "Co-expression of DKK-1 and Sclerostin in Subchondral Bone of the Proximal Femoral Heads from Osteoarthritic Hips." in: Calcified tissue international, Vol. 100, Issue 6, pp. 609-618, (2018) (PubMed).
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- 抗原
- Sclerostin (SOST)
- 别名
- SOST (SOST 产品)
- 别名
- LOC100313724 antibody, CDD antibody, VBCH antibody, 5430411E23Rik antibody, sclerostin antibody, LOC100313724 antibody, SOST antibody, Sost antibody
- 背景
- Sclerostin is a secreted glycoprotein with a C-terminal cysteine knot-like (CTCK) domain and sequence similarity to the DAN (differential screening-selected gene aberrative in neuroblastoma) family of bone morphogenetic protein (BMP) antagonists. Loss-of-function mutations in this gene are associated with an autosomal-recessive disorder, sclerosteosis, which causes progressive bone overgrowth. A deletion downstream of this gene, which causes reduced sclerostin expression, is associated with a milder form of the disorder called van Buchem disease.
- 分子量
- 24031
- 基因ID
- 50964
- NCBI登录号
- NP_079513
- UniProt
- Q9BQB4
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